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Patients taking fluoroquinolones may be at higher risk for ruptures or tears in the aorta

FDA: Fluoroquinolones Tied to Heart Vessel Ruptures, Tears

Patients at risk include those with hypertension or certain genetic disorders and the elderly
For patients initiating oral anticoagulant therapy

Hospitalization for Upper GI Bleed Highest With Rivaroxaban

Upper gastrointestinal bleeding hospitalization risk lower for anticoagulant tx with PPI cotherapy
For patients with recurrent or metastatic head and neck squamous cell carcinoma

Pembrolizumab Promising for Metastatic Head, Neck SCC

Prolongs survival among patients with recurrent, metastatic head and neck squamous cell carcinoma
Sorafenib prolongs progression-free survival among patients with desmoid tumors

Sorafenib for Desmoid Tumors Ups Progression-Free Survival

Two-year progression-free survival rate 81 percent with sorafenib vs. 36 percent with placebo
Patient-centered care is emphasized in updated clinical practice recommendations from the American Diabetes Association 2019 Standards of Care

ADA 2019 Standards of Care Emphasize Patient-Centered Care

Updates include use of SGLT-2 inhibitors and GLP-1 receptor agonists for T2DM, CVD; endorsed by ACC
Black patients with atrial fibrillation are less likely to receive direct-acting oral anticoagulants compared with white patients

Racial Disparities Seen in Use of Oral Anticoagulants for A-Fib

When treated for atrial fibrillation, quality of anticoagulant use lower in blacks, Hispanics
Overall

Prevalence of Benzodiazepine Use 12.6 Percent in the United States

Misuse accounted for 17.2 percent of overall use; highest misuse reported for those aged 18 to 25 years
Almost two-thirds of U.S. women aged 15 to 49 years were currently using contraception in 2015 to 2017

CDC: ~65 Percent of U.S. Women Currently Using Contraceptives

Female sterilization is most commonly used method, followed by oral contraceptive pill
Despite numerous difficulties

Affordable Care Act Sign-Ups Higher Than Expected

As of last Saturday's enrollment deadline, 8.5 million people in 39 states had enrolled
Legacy prescribing of certain drugs

Failure of Timely Stop to Certain Prescription Drugs Is Common

So-called legacy prescribing can contribute to overmedication and adverse drug events