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In older adults

CVD Does Not Modify Depression-Mortality Link in Elderly

Depression tied to higher death risk in older adults; CVD explains just small fraction of excess mortality
An expert panel for the U.S. Food and Drug Administration has endorsed a drug for major depressive disorder that is a close relative to ketamine.

FDA Panel Backs Ketamine-Like Drug for Depression

Esketamine is a nasal spray that targets different pathways in the brain than other antidepressants do
The U.S. Preventive Services Task Force recommends that clinicians provide or refer counseling interventions for pregnant or postpartum women at increased risk for perinatal depression. This recommendation forms the basis of a final recommendation statement published in the Feb. 12 issue of the Journal of the American Medical Association.

USPSTF Recommends Counseling to Prevent Perinatal Depression

Clinicians should provide counseling or referral to high-risk pregnant, postpartum women
Older people who develop depression have significantly slower gait speed and shorter step length several years before diagnosis

Slower Gait Speed, Shorter Step Length Tied to Later Depression

Slowest tertile for gait speed, shortest tertile for step length tied to higher likelihood of depression
Chronic rhinosinusitis is associated with incidence of depression and anxiety

Chronic Rhinosinusitis Linked to Depression, Anxiety

Higher hazard ratios found for depression, anxiety for patients with CRS without nasal polyps
Four maternal characteristics can predict 12-month trajectories for women with postpartum depression with 72.8 percent accuracy

Maternal Factors Predict Postpartum Depression Trajectory

Parity, education, baseline global functioning, depression severity predict chronic severe trajectory
For internal medicine interns

Depressive Symptoms Higher During Internal Medicine Internship

Faculty feedback, learning experience in inpatient rotations, work hours tied to change in symptoms
Objectively assessed physical activity is associated with a protective relationship with major depressive disorder

Objectively Assessed Exercise Protective Against Depression

Objectively assessed, but not self-reported, physical activity protects against major depressive disorder
Therapists implementing interpersonal psychotherapy for depressed adolescents should routinely monitor depression symptoms and consider augmenting treatment for insufficient responders as early as week 4 of treatment

Assessing Symptoms After 4 Weeks of Psychotherapy Helpful in Teens

Week 4 seems better than week 8 for assessing response, implementing treatment augmentation
Recalling specific positive life experiences may build resilience and help lower vulnerability to depression among adolescents with a history of early-life stress

Recalling Positive Memories May Cut Depression Risk for Teens

In teens with early-life stress, positive memory specificity linked to lower depressive symptoms