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Twelfth Version of Living Guideline Issued for Drugs for COVID-19

New update strongly recommends against use of sotrovimab and casirivimab-imdevimab for patients with COVID-19

Full-Dose Anticoagulation Beneficial for Critically Ill With COVID-19

However, no significant difference seen in efficacy or safety outcomes for clopidogrel versus no antiplatelet therapy

Early Aggressive Fluid Resuscitation Not Better for Pancreatitis

Incidence of fluid overload higher, with no improvement in clinical outcomes compared with moderate fluid resuscitation

Umbilical Cord Milking Does Not Reduce NICU Admission

But UCM safe, feasible and may offer some health benefits for nonvigorous infants at birth

More Than Half of ICU Survivors Not Fully Recovered at One Year

Persistent impairment in health-related quality of life seen throughout the year following a critical illness for those not fully recovered

Obstacles, Helpful Behaviors Explored for End-of-Life Care at Critical Access Hospitals

Items associated with family behavior were reported by nurses as the largest obstacles to providing end-of-life care in critical access hospitals

Pressure Injury Prediction Tool Lacking for Severe COVID-19 Patients

Risk factors for device-related pressure injury include fragile skin and prone positioning during mechanical ventilatory support

Protocol Helps Increase Direct Breastfeeding for Preemies in NICU

Increases seen in proportion of infants who had direct breastfeeding at first oral meal, average number of DBF meals during hospitalization

Plasma Viral Antigen Linked to Baseline Severity of COVID-19

High levels of plasma viral antigen linked to outcomes such as worse pulmonary status and longer time to hospital discharge

U.S. Safety-Net Providers Report Moral Distress in Early Pandemic

Moral distress emerged from being unable to provide optimal care, seeing pandemic’s effects on patients, coworkers