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Tag: Cancer: Breast

Genomic recurrence score testing using a 21-gene assay is associated with decreased cancer care costs in real-world practice among certain patients with breast cancer who would otherwise receive standard chemotherapy

Recurrence Score May Cut Costs for High-Risk Breast Cancer Care

Testing with 21-gene assay linked to lower relative, absolute costs among high-risk patients
Only one-quarter of those with breast cancer and one-third with ovarian cancer undergo genetic testing

Genetic Testing Underused in Breast, Ovarian Cancer

Pathogenic variants ID'd in 7.8 percent of patients with breast cancer, 14.5 percent with ovarian cancer
Four evidence-based guidance statements on breast cancer screening have been developed by the American College of Physicians and published online April 9 in the Annals of Internal Medicine.

Guidance Statements Issued for Breast Cancer Screening

Clinicians should discuss mammography with patients aged 40 to 49, discontinue screening for those ≥75
U.S. Food and Drug Administration approval of Ibrance (palbociclib) capsules has been widened to include men with hormone receptor-positive

Ibrance Approval Expanded to Include Men With Breast Cancer

Kinase inhibitor approved in combination with endocrine therapy for male patients with breast cancer
For patients with human epidermal growth factor receptor 2-positive stage IV breast cancer

AACR: Surgery Tied to Improved Survival in HER2+ Breast Cancer

In addition to targeted medication, adjuvant therapy, surgery improves survival in stage IV disease
Dense breast notification laws are associated with increased use of ultrasound and cancer detection only when notification of the possible benefits of supplemental screening is required

State Breast Density Notification Laws May Up Ultrasound Use

But laws should require notification of possible benefits of supplemental screening
Digital breast tomosynthesis can reduce the rate of benign biopsies without affecting cancer detection compared with full-field digital mammography

Digital Breast Tomosynthesis Can Reduce Benign Biopsy Rate

Fewer benign biopsies necessary with DBT compared with full-field digital mammography
Compared with chemotherapy alone

Trastuzumab Tied to Higher Long-Term Risk for Heart Failure

Increased risk for heart failure seen in breast cancer survivors given trastuzumab rather than chemo alone
The correlation between reproductive events and breast cancer risk varies for BRCA1 and BRCA2 mutation carriers

Parity, Risk for Breast Cancer Studied for BRCA1/2 Carriers

Higher risk seen in uniparous BRCA1 carriers, parous BRCA2 carriers; breastfeeding cuts risk in BRCA1
Acupressure is associated with improvements in co-occurring symptoms in breast cancer survivors with fatigue

Acupressure Reduces Lasting Symptoms in Breast Cancer Survivors

Tied to improvements in pain, anxiety, depression among breast cancer survivors with fatigue