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Tag: Cancer: Breast

The U.S. Preventive Services Task Force (USPSTF) recommends screening for women at increased risk for carrying a BRCA1/2 mutation as well as genetic counseling and testing as indicated for those screening positive. These recommendations form the basis of a draft recommendation statement published online Feb. 19 by the USPSTF.

USPSTF Says Screen Women With Higher Risk for BRCA Mutations

Those with positive results should be provided with genetic counseling, testing if indicated
The multigene expression test Oncotype DX is not cost-effective for women with breast cancer who are at low risk for recurrence

Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer

Incremental cost-effectiveness ratio varies across clinical risk groups, sensitive to patient age
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p, p’-DDT Exposure Linked to Breast Cancer Through Age 54

Risk for breast cancer varies based on timing of first exposure, age at diagnosis
From 1989 to 2018

More Than a Half Million Deaths From Breast Cancer Averted

Percent of breast cancer mortality reductions varied from 45.3 to 58.3 percent from 1989 to 2018
Autologous breast reconstruction after failed implant-based reconstruction seems safe and is associated with improved patient outcomes

Outcomes Good for Autologous Reconstruction After Implant Fail

Autologous breast reconstruction associated with improved patient satisfaction, quality of life
Recommendations have been developed to improve accuracy

Use of Image Analysis to ID HER2 Status in Breast Cancer Outlined

Guideline addresses use of quantitative image analysis to interpret HER2 immunohistochemistry
Women with breast cancer have an increased long-term incidence of atrial fibrillation

Long-Term Incidence of A-Fib Increased in Women With Breast Cancer

Women younger than 60 years have increased short-term, longer-term risk
The time to surgery after a breast cancer diagnosis is delayed for non-Hispanic black versus non-Hispanic white women

Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks

Racial differences in TTS did not explain racial differences in overall survival with breast-conserving sx
Among breast cancer patients

Breast Cancer Patients Do Not Overreact to Genetic Testing

No increased cancer worry for multigene panel testing versus BRCA1/2-only test after cancer diagnosis
The U.S. Preventive Services Task Force recommends risk-reducing medications for women at high risk for breast cancer who are at low risk for adverse events

USPSTF Recommends Risk-Reducing Meds for Breast Cancer

Risk-reducing medications recommended for women at high risk, not for routine use