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November 2018 Briefing – Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for November 2018. This roundup includes...
All lots of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide combination blood pressure tablets have been recalled by Teva Pharmaceuticals due to higher-than-acceptable levels of a chemical that may cause cancer.

Teva Recalls Two Blood Pressure Medications

Tablets tainted with N-nitrosodiethylamine, a suspected human carcinogen
Among older patients with polycythemia vera

Recommended Therapies for Polycythemia Vera Underused

Phlebotomy and hydroxyurea tied to improved survival, lower risk for thrombosis in older patients
Vitrakvi (larotrectinib) has been approved by the U.S. Food and Drug Administration to treat adult and pediatric patients whose cancers have a specific genetic feature.

FDA Approves Vitrakvi for Cancers With Certain Genetic Trait

Drug targets solid tumors with NTRK gene fusion without a known acquired resistance mutation
An artificial intelligence-based smartphone app can reduce the severity of cancer patients' reported pain and hospital admissions

AI-Based Smartphone App Can Help Cut Cancer Pain Severity

App can cut both severity of advanced cancer patients' reported pain and hospital admissions
The leading cause of death varies with income in the United States

Heart Disease Leading Cause of Death in Low-Income Counties

Greatest shift to cancer as leading cause of death seen in highest-income counties in United States
There is an urgent need for coordinated

Coordinated Care Needed for Cancer Survivors, Caregivers

Efforts needed in implementing routine assessments of needs, facilitating personalized referrals
Omega-3 fatty acids and vitamin D do not significantly reduce major cardiovascular events or cancer incidence

AHA: Limited Benefit for n-3 Fatty Acids in CVD, Cancer Prevention

Second study shows no significant results for vitamin D supplementation versus placebo
Socioeconomic and health-related behaviors contribute to county-level disparities in cancer deaths

Income, Lifestyle May Contribute to Disparity in Cancer Deaths

In addition to health care factors, issues outside of treatment may affect cancer death rates
Second- and third-generation Latino immigrants have an increased risk for cancer mortality compared with first-generation Mexico-born immigrants

Cancer Mortality Up for 2nd-, 3rd-Generation Latino Immigrants

Latino generation linked to cancer mortality risk after adjustment for education, lifestyle factors, illness