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Antibiotic prescriptions are associated with a higher risk of rheumatoid arthritis

Antibiotic Use Tied to Higher Risk of Rheumatoid Arthritis

Findings show a dose- or frequency-dependent association; all antibiotic classes linked to higher odds for RA
Oral antibiotic use is associated with an increased risk for colon cancer and a reduced risk for rectal cancer

Oral Antibiotic Use Linked to Risk for Colorectal Cancer

Risk for colon cancer increased, risk for rectal cancer reduced in association with oral antibiotic use
More than 85 percent of patients with urinary tract infection receive antibiotics the same day and more than half are treated with trimethoprim

Most U.K. Patients With UTI Receive Antibiotics on Same Day

Represcription rate at 28 days only 4.1 percent from 2011 to 2015; slight increase seen for men over time
Overuse of broad-spectrum antibiotics is associated with increased mortality and other poor outcomes in adults admitted for community-onset pneumonia

Poor Pneumonia Outcomes Tied to Overuse of Broad-Spectrum Antibiotics

Poor outcomes include higher mortality, longer hospital stay, and greater risk for C. difficile infection
Nonprescription antibiotic use appears to be prevalent in the United States

Nonprescription Antibiotic Use Seems Prevalent in the United States

Review shows prevalence varies from 1 to 66 percent depending on population characteristics
For patients with an acute exacerbation of chronic obstructive pulmonary disease

CRP-Guided Testing Cuts Antibiotic Use in COPD Exacerbations

Lower percentage of patients reported antibiotic use, received antibiotic prescriptions
Patients hospitalized with pneumonia often receive excess antibiotic therapy

Hospitalized Pneumonia Patients Often Get Excess Antibiotics

Vast majority of excess treatment occurs with antibiotics prescribed at discharge
Most U.S. adults have heard of and are concerned about antibiotic resistance

Most U.S. Adults Are Concerned About Antibiotic Resistance

However, almost half of survey respondents have not taken antibiotics as prescribed in the past
Antibiotic stewardship interventions for acute respiratory infection can significantly reduce overuse in emergency departments and urgent care centers

Stewardship Intervention Can Cut Inappropriate Rx by a Third

Findings observed for acute respiratory infection in emergency departments and urgent care centers
Children with community-acquired pneumonia often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

Chest radiography ordered in 43 percent, antibiotics prescribed in 73.9 percent of community-acquired pneumonia visits