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Primary care physicians generally do not recognize antibiotic resistance and inappropriate prescribing as issues in their practice

Physicians Do Not See They Are Part of Antibiotic Rx Problem

Providers do not recognize their own inappropriate prescribing, want incentives for stewardship
For patients with gonorrhea

Serine 91 Genotype of gyrA Gonorrhea Successfully Treated With Ciprofloxacin

Efficacy of single-dose oral ciprofloxacin treatment in the per-protocol population was 100 percent
A distance learning program is effective for reducing outpatient prescribing for pediatric acute respiratory tract infection visits

Program Cuts Outpatient Antibiotic Rx for Peds Respiratory Infections

Distance learning program includes online tutorials, webinars; video vignettes; individualized feedback
A 90-second animated video can reduce parents' interest in receiving antibiotics for their child's respiratory infection

Short Video May Lower Parent Interest in Antibiotics for Child

Even bigger impact seen among parents with highest baseline interest in antibiotics
Bacterial and fungal infections are uncommon in hospitalized COVID-19 patients

Bacterial, Fungal Coinfection Uncommon in COVID-19 Patients

Ninety-eight percent of patients received antibiotics at any point during COVID-19 hospitalization
Delayed treatment of upper respiratory tract infections with antibiotics is associated with an increased risk for hospital admissions

Delayed Treatment of Upper Respiratory Tract Infections Tied to Hospitalization Risk

However, delayed antibiotic prescribing was used similarly between high- and low-risk patients
Antibiotic prescription rates are high in low- and middle-income countries

Antibiotic Prescribing High in Low-, Middle-Income Countries

Proportion of patients with inappropriate prescriptions ranged from 8 to 100 percent
Outpatient azithromycin use is associated with an increased risk for cardiovascular and noncardiovascular mortality

CVD, Non-CVD Mortality Increased With Azithromycin Use

Cardiovascular death risk increased within five days of azithromycin exposure, but not at six to 10 days
Doxycycline does not significantly reduce aneurysm growth compared with placebo among patients with small infrarenal abdominal aortic aneurysms

Doxycycline Does Not Cut Growth of Abdominal Aortic Aneurysms

Compared with placebo, no difference seen in growth of small abdominal aortic aneurysms at two years
From 2012 to 2017

Some Multidrug-Resistant Bacterial Infections Down in U.S.

MRSA, vancomycin-resistant enterococcal, MDR P. aeruginosa infection rates fell from 2012 to 2017