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Antibiotic use in children <24 months of age is associated with a slightly higher body weight at 5 years of age

Early Antibiotic Use May Be Tied to Higher Childhood Body Weight

Antibiotics before age 2 associated with very small increase in body weight at 5 years of age
Following the 2007 American Heart Association update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE)

AHA: After 2007 Recs, Increase Seen in Infective Endocarditis

Twenty percent drop in antibiotic prophylaxis, 177 percent increase in IE incidence for high-risk
Almost half of parents report saving leftover antibiotics

AAP: Parents Frequently Save Leftover Antibiotics

Almost three-quarters of those saving antibiotics subsequently divert the antibiotics to others
Prescription of antibiotics and acid-suppressing medications in early childhood is associated with an increased risk for obesity

Antibiotics, Acid Suppressants in Infancy May Up Obesity Risk

Prescription of antibiotics, acid-suppressing meds in first two years of life linked to childhood obesity
For complicated urinary tract infections caused by multidrug-resistant Gram-negative uropathogens

In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens
For patients with staphylococcal bacteremia

Algorithm-Defined Tx Duration Non-Inferior in Staph Bacteremia

Non-inferior rate of clinical success for algorithm defining treatment duration versus usual care
There is considerable variability in the geographic availability of antibiotics

Variability in Geographic Availability of New Antibiotics

Greater geographic availability for antibiotics from and/or marketed by companies in U.S., Europe
For infants with uncomplicated

Low Recurrence With Shortened IV Abx Course in GBS Bacteremia

Some infants with late-onset GBS bacteremia treated with shortened course of IV antibiotics
In a direct-to-consumer telemedicine setting

Telemedicine RTI Visits Shorter When Antibiotic Prescribed

Finding may highlight physician difficulty explaining to patients why antibiotics are not required
The cumulative incidence of appendicitis recurrence within five years is 39.1 percent among patients with uncomplicated acute appendicitis initially treated with antibiotics

Initial Abx Feasible Alternative for Uncomplicated Appendicitis

At five years, cumulative incidence of appendicitis recurrence 39.1 percent with antibiotic treatment