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4.95 Million Deaths Linked to Antimicrobial Resistance in 2019

Lower respiratory infections accounted for >1.5 million deaths associated with resistance, making it the most burdensome syndrome

Risk for Early-Onset Sepsis Low for Infants With Low-Risk Delivery

Risk for early-onset sepsis low among infants of all gestational ages born with low-risk delivery characteristics

Prophylactic Antibiotics Not Needed Before Invasive Dental Procedures

No evidence of temporal association seen between invasive dental procedure and late prosthetic joint infection

Factors ID’d for Eventual Surgery in Patients With Appendicitis

Presence of an appendicolith increases risk for undergoing appendectomy after starting antibiotic therapy for acute appendicitis

Fosfomycin Not Noninferior to Comparators for Bacteremic UTI

Fosfomycin not noninferior to ceftriaxone or meropenem for bacteremic urinary tract infection due to multidrug-resistant E. coli in adults

Pediatric Antibiotic Prescribing Dropped During Pandemic

Decrease in antibiotic prescriptions in pediatric primary care driven by reduced volume of visits for respiratory tract infections

Antibiotic Choices for Skin, Soft Tissue Infections Vary by Race

Compared with White inpatients, Black inpatients less likely to receive cefazolin, more likely to receive clindamycin for SSTIs

SSRIs Linked to Reduced Relative Risk for Mortality in COVID-19

Relative risks for mortality significantly reduced for any SSRI, fluoxetine, and fluoxetine or fluvoxamine

ACS: Surgery May Follow Initial Antibiotic Therapy for Appendicitis

At one and two years, 40 and 46 percent of patients initially receiving antibiotics underwent subsequent appendectomy

Antibiotic Dispensing Decreased After COVID-19 Restrictions

36 percent reduction seen in antibiotic dispensing after COVID-19 restrictions; large reduction found in antibiotics for RTIs