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Tocilizumab may be beneficial for adults with COVID-19 admitted to the intensive care unit

Findings Conflicted for Benefit of Tocilizumab in COVID-19

One trial shows reduction in mortality, but no evidence of efficacy seen in two additional trials
For patients with psoriasis

Survival From COVID-19 High in Patients With Psoriasis

Risk for hospitalization increased for patients using nonbiologic systemic therapy versus biologics
For patients with moderate COVID-19

Convalescent Plasma Has Limited Benefit for Moderate COVID-19

Randomized phase II trial shows no drop in progression to severe disease, all-cause deaths
COVID-19 may not cause a cytokine storm

Cytokines Not at ‘Storm’ Levels in Those With Severe COVID-19

Levels in severely, critically ill COVID-19 patients much lower than in other inflammatory syndromes
A population-based risk algorithm performs well for predicting death and hospital admission due to COVID-19 in adults

Algorithm Predicts Death, Hospital Admission From COVID-19

Final risk algorithm includes age, ethnicity, deprivation, body mass index, range of comorbidities
For moderately ill hospitalized patients with COVID-19

Tocilizumab Does Not Prevent Intubation, Death in COVID-19

Intubation or death, disease worsening similar for tocilizumab, placebo in hospitalized patients
The number of COVID-19-related deaths may be underestimated

CDC: Number of COVID-19 Deaths May Be Underreported

Only two-thirds of the nearly 300,000 excess deaths in 2020 are attributed to COVID-19
The first company to start a phase 3 trial of a COVID-19 vaccine reached its target of enrolling 30

U.S. COVID-19 Vaccine Trial Enrolls 30,000

Moderna says it is on track to apply for FDA approval to market the vaccine in early December
In a move that widens the pool of people considered at risk for COVID-19 infection

CDC Broadens Definition of ‘Close Contact’ in Tracing COVID-19 Infections

Change will likely have biggest impact in group settings where people are in repeated contact with others
Vaccine-related attributes and political characteristics are associated with preference for choosing a hypothetical COVID-19 vaccine

Vaccine Attributes Influence Readiness to Accept COVID-19 Shot

Political considerations also influence preference for choosing a hypothetical COVID-19 vaccine