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Older adults with incident moderately severe dementia living at home have more medical needs than those living in residential care or nursing facilities

Seniors With Dementia at Home Have More Medical Needs

Older adults living at home also more likely to be members of disadvantaged populations
The risk for subsequent dementia is significantly increased for blood pressure patterns of midlife and late-life hypertension as well as midlife hypertension and late-life hypotension; and intensive blood pressure treatment is associated with a smaller increase in cerebral white matter lesion volume

BP From Midlife to Late Life Tied to Risk for Subsequent Dementia

Smaller increase in cerebral white matter lesion volume seen with intensive blood pressure treatment
Taiwanese individuals between the ages of 45 and 64 years old diagnosed with hearing loss are at a greater risk for developing dementia than those without hearing loss

Hearing Loss Increases Risk for Dementia in Taiwanese Individuals

Findings suggest that hearing protection, screening, treatment may help reduce risk for dementia
Adherence to the Life Simple 7 ideal cardiovascular health recommendations in midlife is associated with reduced incidence of dementia later in life

Better CV Health in Midlife Tied to Reduced Dementia Risk Later

Lower risk of dementia with higher Life Simple 7 cardiovascular health score, measured at age 50 years
More frequent social contact during midlife is associated with a lower dementia risk and better cognitive trajectories

More Social Contact at Age 60 Linked to Lower Dementia Risk

More frequent social contact during midlife linked to better subsequent cognitive trajectory
White matter rarefaction

Neuropathology Tied to Dementia ID’d in Football Players Who Had CTE

White matter rarefaction, arteriolosclerosis, DLFC NFTs linked to dementia in football players with CTE
There is a U-shaped association for hemoglobin levels with risk for dementia

U-Shaped Association Found for Hemoglobin Level, Dementia Risk

Similar correlations seen with structural connectivity and white matter hyperintensity volume on brain MRI
Metformin use is associated with a substantially lower risk for dementia among younger African-American patients with diabetes compared with sulfonylurea initiation

Metformin May Lower Dementia Risk in Black Patients With T2DM

Findings strongest in younger African-American patients aged 50 to 64 years
Among elderly patients with prostate cancer

Androgen Deprivation Therapy May Up Risk of Alzheimer Disease

ADT exposure linked to subsequent Alzheimer disease diagnosis among elderly men at eight years
A first-degree family history of dementia is associated with memory deficits decades before the typical onset of Alzheimer disease

Family History of Dementia Tied to Early Memory Deficits

Reduced paired-associates learning performance observed long before typical onset of Alzheimer disease