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Risk Score Developed for RA-Linked Interstitial Lung Disease

Independent risk factors for rheumatoid arthritis (RA)-associated ILD include MUC5B rs35705950 T risk allele, male sex, older age at RA onset

Azathioprine Discontinuation Up for Patients With CC Genotype

Patients with rs2814778-CC also have lower last leukocyte count and lower dosing; findings persist after adjustment for race

Genetic Variants in HMGCR Linked to Increased Cataract Risk

Heterozygous carriers of HMGCR predicted loss-of-function variants had higher risks for developing cataract, cataract surgery

ASCO: Ancestry-Specific Genetic Risk Examined for TNBC

Magnitudes of gene-specific risks for triple-negative breast cancer similar across racial/ethnic groups

ASCO: ctDNA Analysis Guides Treatment of Stage II Colon Cancer

ctDNA-guided approach to determining the need for adjuvant therapy noninferior to standard management for recurrence-free survival

Height May Impact Risk for Disease

Mendelian randomization phenome-wide association study performed to examine relationship between height and clinical traits

ACR: Certain Serious Infections Down for Psoriatic Arthritis Patients

Candidate Biomarkers Identified for Psoriasis Progression

Genomic, proteomic, and metabolomic biomarkers identified from systematic review of relevant studies

Nutrient-Laden Snacks Can Meaningfully Cut Cholesterol

Screening Could Help Identify Familial Hypercholesterolemia

For adults aged 20 to 39 years, clinical criteria alone would yield 1.3 cases per 1,000 screened; adding genetic testing would increase the yield to 4.2 cases

Adherence to Mediterranean-Style Diet May Cut Preeclampsia Risk

Impact of Healthy Lifestyle on GDM Risk Varies With Genetic Risk

Lifestyle intervention effective in reducing age-adjusted occurrence of GDM only among those with the highest genetic risk for type 2 diabetes

Physical Activity Not Tied to Development of Knee Osteoarthritis

Polygenic Risk Score for OA Predicts Risk for Hip, Knee Replacement

Participants with high PRS had increased risk for joint replacement; stronger association seen with hip replacement for women versus men