Tag: Genetics
Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer
Incremental cost-effectiveness ratio varies across clinical risk groups, sensitive to patient age
USPSTF Says Screen Women With Higher Risk for BRCA Mutations
Those with positive results should be provided with genetic counseling, testing if indicated
Improved Genetic Risk Score Aids Type 1 Diabetes Classification
Revised risk score also improves newborn screening versus HLA genotyping alone
Objectively Assessed Exercise Protective Against Depression
Objectively assessed, but not self-reported, physical activity protects against major depressive disorder
Breast Cancer Patients Do Not Overreact to Genetic Testing
No increased cancer worry for multigene panel testing versus BRCA1/2-only test after cancer diagnosis
Hemochromatosis Mutation Linked to Other Morbidity
Higher rates of at least one incident-linked condition seen in men, women with HFE p.C282Y homozygosity
Study Explores Influence of Genetics, Environment in Disease
Genetic component for 40 percent of phenotypes studied; 25 percent have environmental risk factors
Newborn Genomic Sequencing Can Identify Disease Risk
Sequencing detects risk for disorders not anticipated based on infants' known clinical, family history
Three Novel Loci Associated With Polycystic Ovary Syndrome ID’d
Genetic links with obesity, T2DM, lipids suggest shared genetic architecture for PCOS, metabolic traits
Exome Sequencing Provides Genetic Diagnosis for Some With CKD
Genetic diagnosis for 9.3 percent of 3,315 patients with chronic kidney disease from two cohorts
