Tag: Genetics
Diet Less Important Than Genes for High Serum Urate Levels
Certain foods linked to high or low serum urate levels, but dietary scores have limited contribution
Genomic Screening Can ID Undetected BRCA1/2 Cancer Risk
82 percent of variant carriers identified in exome sequencing had not undergone prior testing
Genetics May Identify Type 2 Diabetes Subtypes
Five clusters of T2DM loci and traits, each with distinct tissue-specific enhancer enrichment, identified
Cancer-Related Gene Variations Frequently Reclassified
24.9 percent of variants of uncertain significance were reclassified at a single commercial laboratory
New Risk Factors Identified for Varicose Vein Disease
Mendelian randomization analysis provides evidence that increased height causally tied to varicose veins
Genetic Testing Recommended for Familial Hypercholesterolemia
Expert panel recommends genetic testing as standard of care for definite or probable cases
Worse Health Status With Shorter Telomere Length in COPD
Rate of exacerbation, risk of mortality up with shorter telomere length in placebo-treated patients
Experts Advise Against Universal DNA Sequencing of Newborns
Targeted, whole-exome or whole-genome sequencing can assist in diagnosis of symptomatic infants
Fifteen Genetic Determinants of Fracture Identified
All determinants also associated with bone mineral density, which showed causal effect on fracture
Immune Cells’ Gene Expression May Predict Flu Susceptibility
Expression of KLRD1 by natural killer cells before infection associated with influenza severity
