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Tag: Genetics

B 11/5 Smoking Bans May Not Guard Against Secondhand Smoke: Study

Causal Link Suggested for Smoking, Subarachnoid Hemorrhage

Genetic susceptibility to smoking, assessed using polygenic risk score, is associated with increased risk for SAH

Autistic Traits ID’d in Carriers of CNVs Linked to Autism

54 percent of carriers of certain copy number variants have elevated levels of autistic traits

Review: Nearly One in Five With SARS-CoV-2 Has GI Manifestations

Polygenic Risk Scores May Improve IBD Risk Prediction

For every population in BioMe biobank, combining risk scores from distinct ancestral populations improved risk prediction for IBD

Pembrolizumab Slows MSI-H-dMMR Metastatic CRC

Triple Treatment Combo Beneficial in BRAF-Mutant CRC

Irinotecan, cetuximab, and vemurafenib improve progression-free survival in BRAFV600E-mutated colorectal cancer

U.S. Army Researchers Analyze New Coronavirus Variant

Walter Reed team is checking genetic sequences of the mutated virus variant

Rurality

HFE Hemochromatosis May Up Risk for Liver Cancer in Men

Risk for incident primary hepatic malignancy and death increased among men with HFE p.C282Y homozygosity

Broader Genetic Testing Could ID More Heritable Cancers

ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD

Total hemoglobin, fetal Hb increased in seven patients with transfusion-dependent ß-thalassemia, three with sickle cell disease

Lorlatinib Superior to Crizotinib for ALK-Positive NSCLC

Genetic Ancestry Tied to Lung Cancer Mutations in Latin Americans

Mutation frequencies of EGFR and KRAS were 30 and 10 percent, respectively, and 23 and 13 percent, respectively, for Mexican and Colombian patients

Broader Genetic Testing Could ID More Heritable Cancers

ASH: CRISPR-Cas9 Gene Editing Promising in TDT, SCD

Total hemoglobin, fetal Hb increased in five patients with transfusion-dependent ß-thalassemia, two with sickle cell disease

HealthDay Reports: Black Americans Appear Most Vulnerable to Coronavirus

ASH: Black Race Linked to Poorer Survival in AML

Among AML patients treated on Alliance protocols, Blacks versus Whites had inferior disease-free, overall survival