Tag: Genetics
Platinum Therapy May Up Survival in Pancreatic Cancer With DNA Repair Defects
PFS longer in pancreatic ductal adenocarcinoma with versus without homologous recombination deficiency
Clinical Genetic Testing for Autism Remains Very Low
Based on self-reported data, gap remains between guideline recommendations and clinical practice
Risk for Autism Spectrum Disorder Up With Affected Aunt, Uncle
Rates of ASD higher for offspring of mothers or fathers with a sibling diagnosed with ASD
Multiple Genes Predispose Black Women to Breast Cancer
High risks for breast cancer associated with mutations in BRCA1, BRCA2, PALB2
Link Found Between Body Size in Childhood, Later Life Disease
Larger genetically predicted body size in childhood link to later CAD, T2DM due to large adult body size
High Alcohol Consumption May Be Causally Tied to Stroke, PAD
Some evidence of positive link seen for genetically predicted alcohol consumption with CAD, a-fib, AAA
Clinical, Genetic, Biomarker Model IDs Risk for Pancreatic Cancer
Area under the ROC curve estimated by cross-validation was 0.62 for multifactor model
KL-VSHET+ Genotype Linked to Reduced Alzheimer Disease Risk
Gene variant may be protective in those aged 60 to 80 years, cognitively normal, who carry APOE4
COVID-19 Came to New York City From Europe, Not Asia
Specific genetic codes in most New York City viral samples indicate they originated in Europe
Genetic Testing Does Not Enhance Heart Disease Risk Prediction
Polygenic risk score associated with heart disease events, not a better predictor than standard risk factors
