During study period, 22 percent with GBS had confirmed or probable SARS-CoV-2 infection; patients had uniform neurologic features

Death rates higher in rural areas for both males and females; difference in rates widened during study period

Rates higher for female youth, those with no psychiatric history, and individuals with existing psychiatric diagnoses at time of encounter

Use peaked in January and declined in early 2021, at the time of the vaccine rollout

This happened despite vast gains in scientific knowledge during the past century

Largest annual percentage change seen among Black girls

In 2019, xylazine contributed to death in 64 percent of cases and almost always also involved fentanyl

However, those seeking care delayed care and were less likely to be from sports

The delta variant is driving the increase in hospitalizations

20 of 22 patients with suspected allergic reactions were women; 17 met Brighton anaphylaxis criteria