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Tag: Cancer: Colon

Global burdens of colorectal cancer

Four Studies Look at Global Burden of Digestive Diseases

Global burdens of colorectal, pancreatic, stomach cancers and inflammatory bowel disease examined
Average-risk adults between the ages of 50 and 75 years should be screened for colorectal cancer

CRC Screening Recommended for Average-Risk Adults Age 50 to 75

CRC screening test should be selected based on discussion of benefits, harms, costs with patients
Using the GRADE system to review new evidence

Personal Colorectal Cancer Risk Should Drive Screening

Panel issues weak recommendations for options in adults aged 50 to 79 years with no prior screening
The risk for colorectal cancer death drops with an increasing number of prediagnostic colonoscopies

Prediagnostic Colonoscopy Cuts Colorectal Cancer Death Risk

Mortality risk drops 17 percent with one colonoscopy before diagnosis, 45 percent with three colonoscopies
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy
Delay in referral for colorectal cancer in primary care is associated with low cancer suspicion

Low Cancer Suspicion Tied to Delay in CRC Referral in Primary Care

Presentation without alarm symptoms linked to long duration to referral in multivariable analysis
For patients with colorectal adenomas

High-Intensity Surveillance of Colorectal Adenomas Modeled

Model shows high-intensity surveillance could provide modest, clinically relevant benefits at acceptable cost
There is considerable variability in colorectal cancer mortality disparities across urban cities

Colorectal Cancer Mortality Disparities Vary Across U.S. Cities

Racial disparities in 25 of 30 cities examined; highest disparity in Washington, D.C., lowest in Philadelphia
Among younger adults

Incidence of Colorectal Cancer Up in Younger Adults Worldwide

In most high-income countries with long-term data, uptick in early-onset disease began in mid-1990s
For patients with advanced/metastatic colorectal cancer

Physical Activity, Overall Survival Not Linked in Metastatic CRC

Nine or more MET hours per week tied to lower risk for grade ≥3 treatment-related adverse events