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Tag: Cancer: Colon

After the first round of a fecal immunochemical test-based

Negligible Drop in Neoplastic Lesion Dx After First Round of FIT

Negligible reduction in neoplastic lesion detection in proximal versus distal colon after first round of FIT
Programmatic sensitivity for colorectal cancer detection increases modestly with decreasing fecal immunochemical test positivity thresholds

Sensitivity for CRC Detection Up With Decreasing FIT Threshold

Reducing positivity threshold also increased number of positive test results per cancer case
In accordance with the U.S. Preventive Services Task Force

AAFP Still Recommends CRC Screening From Age 50 to 75

Despite ACS change to start screening from age 45 years, AAFP agrees with USPSTF recommendation
Higher circulating levels of vitamin D are tied to significantly lower colorectal cancer risk

Higher Vitamin D Levels Tied to Lower Risk of Colorectal Cancer

In women, risk declines as levels increase up to 100 nmol/L, but association in men not significant
Costs of treatment for metastatic colorectal cancer are significantly higher in Western Washington State than in British Columbia

ASCO: mCRC Costs Up in Western Washington vs. British Columbia

No significant difference between regions in median OS for those receiving, not receiving systemic tx
Colorectal cancer screening should begin at age 45 for people at average risk

ACS Updates Colorectal Cancer Screening to Start at Age 45

Average-risk adults aged 45+ should undergo high-sensitivity stool-based test, structural exam
For patients with colorectal cancer after curative surgery

Surveillance Frequency Doesn’t Cut Mortality in Colorectal Cancer

And, intensity of imaging surveillance not linked to time to detection of colorectal cancer recurrence
For patients undergoing resection of colorectal liver metastases

V600E BRAF Mutation Tied to Worse Survival in CRC Liver Mets

Worse overall, disease-free survival with V600E BRAF versus KRAS mutation in colorectal liver metastases
Participants with an advanced adenoma at diagnostic colonoscopy have increased risk of developing colorectal cancer relative to those with no adenoma

Higher CRC Risk With Advanced Adenoma Found on Colonoscopy

Risk not increased for non-advanced adenoma found on colonoscopy following flex sigmoidoscopy
The introduction of public reporting of surgeon specific 90-day postoperative mortality in elective colorectal cancer surgery is associated with a reduction in observed 90-day mortality

Reporting Outcomes Per Surgeon Tied to Drop in CRC Sx Mortality

Reduction in mortality with intro of public reporting of surgeon specific 90-day post-op mortality