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November 2018 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for November 2018. This roundup includes...
Energy control and food source appear to mediate the effect of fructose-containing sugars on glycemic control

Impact of Fructose Varies With Energy Control, Food Source

Harmful effects for sugar-sweetened beverages when excess energy from sugar added to diet
About one in four patients report cost-related insulin underuse

Cost-Related Insulin Underuse May Affect One in Four Patients

Patients reporting cost-related underuse more likely to have poor glycemic control
Participation in the Supplemental Nutrition Assistance Program may reduce the number of low-income older adults with diabetes forgoing medications because of cost

Food Assistance May Help Older Adults Adhere to Diabetes Meds

Food assistance may cut number of older adults with diabetes forgoing medications due to cost
For patients with diabetes

Switching to High-Deductible Insurance Delays Diabetes Care

Delays in seeking care for first major symptom of macrovascular disease, first major diagnostic test
Diabetes outcomes do not differ for patients treated with a primary care provider who is either a physician

NPs and PAs Can Effectively Manage Diabetes in Primary Care

No difference in HbA1c, SBP, LDL-C with doctor, nurse practitioner, physician assistant
Use of sodium glucose cotransporter 2 inhibitors is associated with an increased risk for lower-limb amputation and diabetic ketoacidosis compared with use of glucagon-like peptide 1 receptor agonists

Higher Risk for Amputation, DKA With SGLT2 Inhibitors for T2DM

Risk increased for lower-limb amputation, diabetic ketoacidosis compared with GLP1 receptor agonists
For patients with diabetes mellitus with multivessel coronary disease

AHA: Lasting Benefit for CABG in Diabetes, Multivessel Disease

Lower all-cause mortality in CABG group versus PCI-DES group after median follow-up of 7.5 years
More than one-third of Americans have prediabetes

CDC: Many Americans May Have Prediabetes and Not Know It

AMA, CDC launch a campaign to raise awareness about prediabetes
Individuals with Alzheimer's disease have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway

Abnormalities in Genes Linked to IRSP in Alzheimer’s Disease

Abnormalities, reductions in gene expression associated with insulin receptor signaling pathway