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Slow-release implantable naltrexone is associated with better outcomes than the oral drug for HIV-positive patients with an opioid addiction

Naltrexone Implant Helps HIV Patients Prevent Opioid Relapse

Compared with oral naltrexone, implant also improved HIV outcomes among those with opioid dependence
Men receiving 5α-reductase inhibitors have an increased risk for new-onset type 2 diabetes mellitus

Risk for T2DM Increased With Use of 5α-Reductase Inhibitors

Increased risk seen among men using dutasteride, finasteride for benign prostatic hyperplasia
Monotherapy with UB-421 antibody

UB-421 Monotherapy Maintains HIV Viral Suppression

Suppression maintained for up to 16 weeks in HIV-infected undergoing analytic treatment interruption
The overall burden of outpatient parenteral antimicrobial therapy is substantially higher than that of oral therapy for caregivers of children on prolonged antimicrobial therapy after hospital discharge

Parenteral Antimicrobial Tx at Home Burdens Children’s Caregivers

Compared with those who receive oral therapy, caregivers miss more work, have lower QoL scores
For patients with chronic myeloid leukemia

Reasons for TKI Discontinuation ID’d in Chronic Myeloid Leukemia

Treatment-free remission maintained in 14 of 21 patients who discontinued tyrosine kinase inhibitors
Antiepileptic drug use may increase the risk for pneumonia in patients with Alzheimer disease

AEDs Tied to Higher Pneumonia Risk in Alzheimer Patients

Risk for pneumonia highest within first month of antiepileptic drug use but persists through two years
Canagliflozin is associated with a reduced risk for renal and cardiovascular events for patients with type 2 diabetes and kidney disease

Canagliflozin Seems Effective for Patients With T2DM, Kidney Disease

Reductions seen in risk for kidney failure, cardiovascular disease with canagliflozin versus placebo
Medication shortages are frequently reported by pharmacy practice managers

Pharmacy Practice Managers Report Frequent Drug Shortages

More than one-third of respondents reported no administrative methods for responding to shortages
Peripheral nerve blockade with regular local anesthetic and liposomal bupivacaine is associated with lower oral morphine equivalent use at 72 hours after major lower extremity amputation

Peripheral Nerve Block May Cut Opioid Use After Amputation

Peripheral nerve block helps improve pain control after major lower extremity amputation
Use of the orally administered β-site amyloid precursor protein-cleaving enzyme 1 inhibitors

Verubecestat, Atabecestat Not Beneficial for Preventing Alzheimer Disease

Two trials show lack of effectiveness versus placebo for preclinical Alzheimer disease