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Lanifibranor Reduces Disease Activity in Nonalcoholic Steatohepatitis

In phase 2b trial, more patients with active NASH had reduction in disease activity score with lanifibranor versus placebo

Avoid Intensification of Diabetes Meds at Discharge in Older Adults

For older adults hospitalized with common medical conditions, intensifying diabetes meds at time of discharge shows little benefit

Psoriatic Arthritis May Up Risk for Preterm Birth, C-Section

Risk for preterm birth increased with antirheumatic treatment for psoriatic arthritis -- particularly biologics -- during pregnancy

AHA Provides Strategies to Improve BP Medication Adherence

Interventions for effective med adherence include patient education and counseling, simplification of treatment regimens

FDA Approves First Interchangeable Biosimilar for Inflammatory Diseases

Cyltezo is first interchangeable monoclonal antibody for RA, psoriatic arthritis, ankylosing spondylitis, Crohn disease, ulcerative colitis, chronic plaque psoriasis

Varenicline Combo, Extension No Better for Quitting Smoking

Combining varenicline with nicotine patch, extending treatment from 12 to 24 weeks did not increase smoking cessation rates

Pharmacies Often Not Notified of Discontinued Rx

Interventions, including phoning pharmacies and enabling CancelRX in electronic medical records, may reduce risk for medication safety events

Ozanimod Beats Placebo for Ulcerative Colitis

Once-daily oral ozanimod more effective than placebo for moderately to severely active ulcerative colitis

SGLT2 Inhibitors May Cut Risk for Heart Failure Hospitalization

SGLT2 inhibitors, compared with GLP-1 RAs, linked to lower risk for heart failure hospitalization in patients with T2DM, with or without CVD

Abiraterone Acetate + Prednisone Cuts Metastasis in Prostate Cancer

And standard of care plus abiraterone improves survival in men with metastatic castration-sensitive prostate cancer