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Patients with primary restless leg syndrome who begin dopamine agonist therapy may be at increased risk for adverse psychiatric events

Dopamine Agonists Tied to Higher Risk for Psychiatric Events

Findings seen in large study of patients with restless leg syndrome starting dopamine agonists
Tesamorelin reduces liver fat content in patients with HIV and nonalcoholic fatty liver disease

Tesamorelin May Aid Patients With HIV, Fatty Liver Disease

Tesamorelin significantly reduced hepatic fat fraction compared with placebo
After one year of therapy with lumacaftor-ivacaftor in a real-world setting

Lumacaftor-Ivacaftor Aids Cystic Fibrosis in Real-World Setting

Improved lung function, increased BMI, reduced need for IV antibiotics seen after one year of therapy
Most dimensions of quality of life (QoL) are impaired in patients with relapsed/refractory multiple myeloma

Effects on Quality of Life Mixed for Tx of Multiple Myeloma

Reduced pain but worsening of neuropathy seen for IxaThalDex induction tx in relapsed/refractory MM
Ibrutinib is associated with an increased risk for new or worsened hypertension in patients treated for B-cell malignancies

Ibrutinib Therapy Linked to New, Worsened Hypertension

Ibrutinib-related hypertension associated with increased risk for major adverse cardiovascular events
A class of diabetes drugs

SGLT2 Inhibitors Protect Against Kidney Disease in T2DM

Reduction seen for risk of dialysis, transplantation, or death due to kidney disease
The poly(adenosine diphosphate-ribose) polymerase inhibitor veliparib plus platinum-based chemotherapy for induction therapy

PARP Inhibitor Slows Progression of Advanced Ovarian Cancer

Veliparib added to chemotherapy, continued as maintenance tx prolongs progression-free survival
Hydroxychloroquine blood levels are useful in predicting retinopathy among patients with systemic lupus erythematosus

Hydroxychloroquine Blood Levels Predict Retinopathy Risk in Lupus

Prospective cohort study demonstrates link between HCQ blood levels and retinopathy risk
Over-the-counter medications are commonly used in suicide attempts by self-poisoning among young people

OTC Meds Often Used in Drug-Related Suicide Attempts in Youth

ADHD meds commonly used by those aged 10 to 15 years, while sedative/hypnotics used more by older youth
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy