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Dupilumab Tied to Fewer Exacerbations in COPD With Type 2 Inflammation

Increase seen in prebronchodilator forced expiratory volume in one second with dupilumab versus placebo at weeks 12, 52

Semaglutide Has Lasting Benefit for Weight Loss

Second study shows cardiovascular benefit for semaglutide, regardless of weight loss

Fezolinetant Safe, Effective for Moderate-to-Severe Menopause Hot Flashes

Benefits seen within days for both frequency and severity of symptoms

Bisoprolol Does Not Reduce Exacerbations in At-Risk COPD Patients

No reduction seen in number of self-reported exacerbations treated with oral corticosteroids, antibiotics, or both

Aficamten Beneficial for Obstructive Hypertrophic Cardiomyopathy

Significantly greater improvement seen in peak oxygen uptake with aficamten versus placebo for symptomatic HCM

Oldest Adults With Acute Myeloid Leukemia Benefit From Venetoclax

Octogenarians and nonagenarians can be treated successfully with VEN-HMA

Mail-Order Mifepristone Effective, Feasible for Medication Abortion

Mail-order pharmacy dispensing of mifepristone after in-person screening effective, with low prevalence of serious adverse events

Study Identifies Factors Associated With Hydroxychloroquine Retinopathy

Increased risk seen in association with female sex, older age, CKD stage 3 or greater, tamoxifen use

Cytisinicline Beneficial for Cessation of Electronic Cigarette Smoking

Significantly more patients receiving cytisinicline versus placebo had continuous e-cigarette abstinence at the end of treatment

Some Children Prescribed Nonrecommended Meds for COVID-19

Some children were prescribed ineffective and potentially harmful medications for acute COVID-19