Tag: Prescription Drugs
Prenatal Fluconazole Exposure Increases Neonatal Risks
Any exposure increases spontaneous abortion risk; cardiac septal defects up for use in early pregnancy
Early Intensive Treatment May Improve Long-Term MS Outcomes
Mean five-year change lower in Expanded Disability Status Scale score with early intensive treatment
Combo Regimens Effective for Tx of Metastatic Renal Cell Cancer
Two large trials show benefits for pembrolizumab-axitinib and avelumab-axitinib versus sunitinib
Inappropriate Use of Fentanyl Preps Seen Despite Awareness
Claims data show many prescribed transmucosal immediate-release fentanyl were opioid-nontolerant
Darolutamide Slows Spread of Castration-Resistant Prostate Cancer
Significant survival benefit seen, adverse events similar between darolutamide and placebo
Rates of Osteonecrosis of the Jaw Low for Denosumab-Treated Women
Invasive oral procedures associated with increased incidence of ONJ, but rate low overall
Drug Company Payments Over Time May Influence Rx Practices
Payment consistency, high amount, compensation payments tied to cancer drug prescribing practices
FDA Panel Backs Ketamine-Like Drug for Depression
Esketamine is a nasal spray that targets different pathways in the brain than other antidepressants do
Direct-Acting Antivirals Cut Mortality in Chronic Hepatitis C
Mortality, hepatocellular carcinoma risk reduced after adjustment for potential confounders
ASA: Reversal Agent Cuts Severe Bleeding With Factor Xa Inhibitors
Bolus plus two-hour infusion of andexanet alfa cuts antifactor Xa activity by 92 percent