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For women with early breast cancer receiving anthracyclines or trastuzumab

ACC: Statins Cut Heart Failure Risk in Early Breast Cancer Treatment

Risk for heart failure hospital visit declined with statins for women receiving anthracyclines, trastuzumab
Amongpatients with multidrug-resistant HIV-1 infection who have limited therapy options

Fostemsavir Active in Multidrug-Resistant HIV-1 Infection

Reduction in HIV-1 RNA level significantly greater for fostemsavir versus placebo in randomized cohort
For patients with transfusion-dependent β-thalassemia

Reduction Noted in Transfusion Burden With Luspatercept

Reduction seen with luspatercept versus placebo for patients with transfusion-dependent β-thalassemia
Following severe criticism

Gilead Backs Down on Special Designation for Possible COVID-19 Drug

Pharmaceutical company had asked the FDA to designate remdesivir an 'orphan drug'
Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions

FDA Warns of Defective EpiPen Dangers

Devices may activate prematurely if the blue safety release is removed using sideways force
One in 10 older adults hospitalized for common medical conditions are discharged with intensified diabetes medications

Many Older Adults Receive Inpatient Diabetes Rx Intensification

Benefit unlikely in half due to limited life expectancy or already being at their HbA1c goal
Inhibition of interleukin-1β with canakinumab is associated with reduced incident anemia as well as improved hemoglobin levels among patients with baseline anemia

Interleukin-1β Inhibition Linked to Reduced Incidence of Anemia

Among those with baseline anemia, hemoglobin levels improved with canakinumab versus placebo
Strong demand for medications that show promise as treatments for COVID-19 have led to shortages of those drugs in the United States.

Shortages Seen for Drugs That Show Promise Against COVID-19

Patients who currently rely on remdesivir or hydroxychloroquine now facing dangerous shortages
A once-daily

Triple Therapy Cuts Mortality in Patients With Symptomatic COPD

All-cause mortality risk significantly lower for triple-drug regimen versus one of two dual-drug regimens
Iron chelation therapy seems beneficial for iron-overloaded patients with low- or intermediate-1-risk myelodysplastic syndromes

Iron Chelation Therapy Treats Iron Overload in MDS

Event-free survival prolonged with ICT for patients with lower-risk myelodysplastic syndromes