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Compared with insulin glargine

ADA: Combo Injectable Controls Blood Glucose Longer in T2DM

Findings seen for initial injectable therapy with insulin degludec plus liraglutide versus insulin glargine
There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy

Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

Findings seen among Dutch children exposed to one of four common antiepileptic drugs in utero
A 14-day course of an Fc receptor-nonbinding anti-CD3 monoclonal antibody

ADA: Teplizumab Can Delay T1DM Progression in Those at Risk

Median time to type 1 diabetes diagnosis 48.4 months with teplizumab and 24.4 months with placebo
For left ventricular assist device recipients

PDE5i Use Linked to Post-LVAD Right Heart Failure Events

Incidence of severe early right heart failure higher among patients on preimplant PDE5i than controls
Valproic acid and topiramate are confirmed teratogens

Study Confirms Teratogenicity of Valproic Acid, Topiramate

Eight specific types of major congenital malformations associated with prenatal exposure to valproic acid
Dulaglutide is associated with a reduction in cardiovascular events and renal outcomes among patients with type 2 diabetes

ADA: Dulaglutide Tied to Decline in Cardiovascular Events in T2DM

Second study shows reduction in renal outcomes with dulaglutide in type 2 diabetes
The U.S. Preventive Services Task Force recommends preexposure prophylaxis and HIV screening for prevention of HIV infection. These recommendations form the basis of two final recommendation statements published online June 11 in the Journal of the American Medical Association.

USPSTF Issues Recommendations on HIV Screening, Prevention

Recommendations support PrEP for those at high HIV risk, screening for teens, adults, in pregnancy
There is variability in data relating to the safety of lithium during breastfeeding

Data Insufficient for Safety of Lithium During Breastfeeding

Lithium transfer to infants is variable; three cases of adverse effects reported, but confounding occurred
Nonmedical use of alprazolam is a significant issue in the United Kingdom

Misuse of Alprazolam Common in the United Kingdom

Survey shows nonmedical use of the antianxiety drug is most common among younger adults
Only one-third of Philadelphia pharmacies carry naloxone nasal spray and many pharmacies require a physician's prescription

Naloxone Available in One in Three Philadelphia Pharmacies

In chain stores, naloxone was more likely to be in stock and to be available without a prescription