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Implementation of rotavirus vaccination has reduced disease prevalence and season duration in the United States

Rotavirus Vaccine Led to Reduced Disease Prevalence, Season Duration

In postvaccine period, a biennial pattern emerged with alternating years of high, low disease activity
Children with nonchromosomal birth defects have a higher relative risk for cancer

Nonchromosomal Birth Defects May Up Childhood Cancer Risk

Study identified 40 significant, specific associations between birth defects and childhood cancer
Anxiety is independently associated with high-cost resource use among individuals with type 2 diabetes

Anxiety With Type 2 Diabetes Tied to High-Cost Health Care Use

Anxiety and type 2 diabetes related to frequent visits to ED, high costs but not total hospitalization costs
The incidence of infection increases with glucocorticoid dose for patients with polymyalgia rheumatica or giant cell arteritis

Oral Steroids Increase Infection Risk in Inflammatory Disease

Dose-response effect seen with increased infection risk even at low daily doses of oral glucocorticoids
Transfusion dose density is an independent prognostic factor for progression-free survival in patients with myelodysplastic syndromes treated with red blood cell transfusions

Transfusion Dose Density Affects Myelodysplastic Syndrome Survival

Negative effect of transfusion treatment on PFS occurs at density less than 3 units/16 weeks
Infants who are given acid suppression therapy in their first year of life are more likely to subsequently break a bone

Antacid Use in First Year of Life Tied to Later Fracture Risk

Findings seen among healthy infants taking proton pump inhibitors alone or with histamine H2-receptor antagonists
More than 2 percent of suicides among adults 55 years and older are associated with patients living in or transitioning to long-term care

Suicide Risk Seen Among Older Adults Living in Long-Term Care

Mental health and well-being of older adults should be addressed in these settings, authors say
The decline in midlife ischemic strokes over time is less pronounced than the decline among older adults

Greater Long-Term Decline in Stroke Seen Among Older Adults

Continued focus on prevention efforts needed to lower risk for midlife ischemic strokes
Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients with PIK3CA-mutated

Drug Combo Slows Progression in Advanced Breast Cancer

Results seen for alpelisib plus fulvestrant in PIK3CA-mutated, HR+, HER2− advanced breast cancer
Vyleesi (bremelanotide) has been approved to treat acquired

Vyleesi Approved for Hypoactive Sexual Desire Disorder in Women

FDA approved Vyleesi for premenopausal women; drug administered by subcutaneous injection