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In an evidence-based clinical guideline

Guidelines Developed for Care of Adults With Down Syndrome

Strong recommendation advises screening for Alzheimer-type dementia starting at age 40 years
Flavan-3-ol intake is associated with lower systolic blood pressure

Flavan-3-ol Intake Appears to Lower Systolic Blood Pressure

Reduction comparable to adherence to Mediterranean diet or moderate reduction in salt
Patients admitted for hemorrhagic stroke on weekends have higher in-hospital mortality than those admitted on weekdays

Weekend Admission Tied to Higher Stroke Mortality

Admission for hemorrhagic stroke on weekends versus weekdays tied to higher mortality at both rural, urban hospitals
Exposure to maternal hypothyroidism during the periconceptual period is associated with an increased risk for childhood attention-deficit hyperactivity disorder in offspring

Maternal Hypothyroidism Linked to Risk for ADHD in Offspring

Risk for ADHD increased in children of mothers with hypothyroidism diagnosed prior to, during pregnancy
Patients with new-onset focal epilepsy with subtle seizures experience prolonged time to diagnosis

Time to Diagnosis Longer for Subtle Seizures in Focal Epilepsy

Most related motor vehicle accidents tied to new-onset focal epilepsy in those with subtle seizures
For adolescents and young adults with anorexia nervosa or atypical anorexia nervosa

Higher-Calorie Refeeding Beneficial in Anorexia Nervosa

Medical stability restored significantly earlier; no increase seen in electrolyte abnormalities, adverse events
Long-term survival analysis shows that patients with earlier initiation of sodium phenylbutyrate-taurursodiol treatment for amyotrophic lateral sclerosis have longer median overall survival

Investigational Drug May Prolong Survival in Patients With ALS

Median survival 6.5 months longer with initiation of PB-TURSO treatment compared with placebo
Neurologic disorders are not uncommon in hospitalized COVID-19 patients

Neurologic Complications Seen in Hospitalized COVID-19 Patients

Neurologic disorders tied to increased risk for in-hospital mortality
Children with autism spectrum disorder and/or attention-deficit/hyperactivity disorder have more doctor and hospital visits during infancy

Autism, ADHD Linked to More Doctor, Hospital Visits by Age 1

Patterns of health care use before age 1 distinctive in autism, attention-deficit/hyperactivity disorder
For older adults

Social Activity Tied to Integrity of Brain Structure in Older Adults

Greater integrity of gray matter seen on brain MRI in older adults with higher levels of social engagement