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Patterns of potential opioid misuse are positively associated with subsequent opioid overdose

Patterns of Potential Misuse Help Assess Risk of Opioid Overdose

Positive link for subsequent opioid overdose with greater numbers of prescribers and pharmacies
Patients undergoing urological procedures use just over half of their initial prescription of opioids

AUA: Many Have Unused Opioids After Urologic Procedures

Patients use just over half of initial prescription; highest percentage of unused meds for cystectomy
Lucemyra (lofexidine hydrochloride) has been approved by the U.S. Food and Drug Administration to treat symptoms of opioid withdrawal.

FDA Approves Non-Opioid Treatment for Opioid Withdrawal

Lucemyra is an oral selective alpha 2-adrenergic receptor agonist
An intervention targeting the use of intravenous opioids may reduce opioid exposure

Practice Intervention Targeting IV Opioids May Cut Exposure

Reduction of 84 percent in intravenous opioid doses, and a 55 percent reduction in all parenteral opioids
There is insufficient evidence available for examining the correlation between prescription drug monitoring programs and non-fatal or fatal overdoses

Evidence Lacking for Impact of PDMPs on Drug Overdoses

Evidence insufficient that drug monitoring programs increase or decrease opioid overdoses in U.S.
Many patients undergoing elective same-day or inpatient joint and spine surgery have unused opioids at one- and six-month follow-up

Many Patients Have Unused Opioids After Spine, Joint Surgery

Many patients reported unsafe storage and failure to dispose of opioids at one- and six-month follow-up
Patients use fewer opioids than are prescribed after hiatal hernia repair

Opioids Often Over-Prescribed After Hiatal Hernia Surgery

Patients use fewer opioids than are prescribed after open, laparoscopic hiatal hernia repair
Synthetic opioid involvement in opioid-related overdose deaths increased significantly from 2010 to 2016

Synthetic Opioid Involvement in Opioid-Related Deaths Up

From 2010 to 2016, synthetic opioid involvement up from 14.3 to 45.9 percent of opioid-related deaths
Patients with opioid use disorder seem to have a high rate of suicide

People With Opioid Use Disorder Have High Suicide Rate

Based on data from multiple sources, many opioid-overdose deaths seem to be suicides
For patients undergoing head and neck cancer surgery

Celecoxib Lowers Opioid Use Post Head & Neck Cancer Surgery

Decreased opioid use seen after head and neck cancer surgery with free tissue reconstruction