Home Tags Opioids

Tag: Opioids

Purdue Pharma

Purdue Pharma to Plead Guilty to Opioid-Related Crimes

Settlement is federal government's biggest win in holding a major drug company responsible for opioid crisis
Evidence-based guidelines successfully reduce postoperative opioid prescribing without increased refill rates

One Size May Not Fit All for Postoperative Opioid Prescribing

Guidelines reduce postoperative opioid prescribing but may result in inadequate pain control for some
For U.S. adults with problem substance use who use nonmedical opioids

For Substance Abusers, Odds of Opioid Use Up With Cannabis Use

For adults using nonmedical opioids, odds of opioid use are increased on days when cannabis is used
Prescription pain medication abuse decreased significantly from 2007 to 2018

ASA: Sustained Decrease Seen in Prescription Opioid Abuse in U.S.

Significant declines seen from 2002 to 2013 and 2014 and from 2015 to 2016, 2017, 2018
Opioids prescribed by dentists may pose a threat for interactions with medications for depression or anxiety in older adults

Dentists’ Rx for Opioids Pose Danger for Drug Interactions

In older adults, interactions with meds for depression, anxiety increase risk for ED visits, hospitalizations
New drug applications for prescription opioids for pain have been based on pivotal trials of short or intermediate duration

New FDA Applications for Opioids Often Based on Short Trials

Most products for treating chronic pain approved based on narrowly defined populations of patients
More than 83 percent of overdose deaths during January to June 2019 involved illicitly manufactured fentanyls

One or More Opioids Involved in ~80 Percent of OD Deaths

At least one potential opportunity for prevention intervention for 62.7 percent of overdose deaths
An enhanced recovery after surgery program for cesarean delivery is associated with improved outcomes

Enhanced Recovery Approach Aids Cesarean Birth Outcomes

Benefits of enhanced recovery after surgery program include decreases in opioid use, length of stay, and costs
The TEACH (Targeting Effective Analgesia in Clinics for HIV) intervention is a promising strategy for improving adherence to opioid prescribing guidelines among HIV care providers and their patients on chronic opioid therapy

Program Improves Use of Chronic Opioid Therapy in HIV Care

TEACH intervention increases adherence to guideline-concordant care for HIV patients with chronic pain
About half of waivered clinicians prescribe buprenorphine for opioid use disorder and most treat at levels below their patient limits

About Half of Waivered Clinicians Prescribe Buprenorphine for OUD

Percentages much higher for actively prescribing U.S. clinicians with 275 and 100 versus 30 patients