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Initiation of isoniazid preventive therapy during pregnancy is associated with increased risks versus initiation during the postpartum period

Isoniazid Tx to Prevent TB Ups Risks During HIV+ Pregnancy

Deferring treatment until after delivery appears to be safer option
Medical devices that can connect to the internet might be at risk for hacking

FDA: Pacemakers, Insulin Pumps Could Be Hacking Targets

Cyberattackers could take control of a medical device and cause it not to work properly or at all
Some nutrient supplements may be beneficial as adjunctive treatment for common mental health conditions

Some Nutritional Supplements May Aid Mental Health Conditions

Nutrient supplements had good safety profiles, no known contraindications with psychiatric medications
Compared with placebo

No Benefit Found for High-Dose Vitamin C Infusions in Sepsis, ARDS

No differences seen versus placebo in organ dysfunction scores, biomarkers of inflammation or vascular injury
Elderly patients with inflammatory bowel disease are at higher risk for adverse events related to the use of thiopurines

Elderly Who Start Thiopurine Tx for IBD Have Higher Risk for AEs

Advanced age, female gender are independent risk factors for adverse events
Uptitration of drugs for chronic systolic heart failure stops farther away from the recommended dosage for drugs with higher versus lower recommended dosages

Uptitration of Drugs Varies With Target Dosage in Chronic HF

When target is higher versus lower dosage, uptitration stops further from recommended dosage
Marine omega-3 supplementation seems to lower the risk for myocardial infarction

Marine Omega-3 Supplements May Lower CVD Risk

Updated meta-analysis shows lower risks for MI, CHD death, total CHD, CVD death, total CVD
For adults with type 1 diabetes

Glycemic Control Worse Than Thought in Adults With T1DM

Rates of both acute and chronic complications significantly increase with increasing HbA1c

September 2019 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for September 2019. This roundup includes the latest...
For patients with progressive fibrosing interstitial lung diseases

Nintedanib Slows Fibrosing Interstitial Lung Disease

Nintedanib linked to lower rate of decline in forced vital capacity versus placebo in phase 3 trial