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Hematology and Oncology

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A case of acquired syphilis leading to involvement of the bone marrow and liver is described in a report published online March 22 in the Annals of Internal Medicine.

Report of Bone Marrow/Liver Pathology Caused by Syphilis

Case study describes 65-year-old patient with late-latent syphilis with normocytic anemia
The American Society of Clinical Oncology has endorsed the Cancer Care Ontario recommendations on the role of patient and disease factors in selecting adjuvant therapy for early-stage breast cancer

ASCO Endorses Cancer Care Ontario Breast Cancer Guidelines

Several patient, disease factors should be considered for adjuvant therapy for early breast cancer
Interpretation of a single breast biopsy slide per case predicts low likelihood of verification for diagnosis of atypia or ductal carcinoma in situ

Low Likelihood for Atypia, DCIS Verification With Single Slide

Highly probable verification for invasive breast cancer and benign without atypia diagnoses
For patients with familial adenomatous polyposis

Drug Combo Reduces Polyps in Familial Adenomatous Polyposis

Findings for sulindac twice daily and erlotinib daily
For women aged younger than 50 years

Poor Prognosis for Women With Pregnancy-Associated Melanoma

Among women aged up to 49 years, invasive melanoma less common in those 19 years or younger
Intra-arterial chemotherapy appears to be promising for intraocular retinoblastoma

Intra-Arterial Chemo Promising for Intraocular Retinoblastoma

Global salvage achieved for 66 percent of all eyes across 12 single-arm cases series studies
Physicians have responded to the new U.S. Centers for Disease Control and Prevention's clinical guidelines for prescribing opioids

Physicians Respond to New CDC Opioid Guidelines

Mainly supportive of guidelines, but concerns include lack of evidence underlying recommendations
A genetic test of homologous recombination genes might help predict outcomes for women diagnosed with ovarian cancer

Gene Panel Test May Help Predict Ovarian Cancer Prognosis

Women with mutations in some 'DNA repair' genes may survive much longer, research shows
The U.S. Food and Drug Administration wants to ban most powdered medical gloves

FDA: Most Powdered Medical Gloves Should Be Banned in U.S.

Side effects include airway and wound inflammation, agency says
A rare case of immobility-induced hypercalcemia in an infant has been documented in a case report published online March 18 in Pediatrics.

Case Report: Immobility-Induced Hypercalcemia in Infant

Infant presented with fatigue, irritability, failure to gain weight after prolonged immobilization