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Diabetes and Endocrinology

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Caloric restriction improves peripheral insulin sensitivity

TXNIP May Mediate Insulin Sensitivity in Caloric Restriction

Better peripheral insulin sensitivity tied to reduction in insulin-stimulated thioredoxin-interacting protein
Metformin is associated with a lower risk of developing head and neck cancer in patients with diabetes

Metformin Linked to Lower Risk of Head, Neck Cancer

Diabetes patients treated with the drug less likely to develop oropharyngeal, nasopharyngeal cancers
Regardless of weight loss

Bariatric Surgery Beats Drug Tx for Metabolic Outcomes in T2DM

Surgery associated with significantly lower plasma lipids, CV risk, medication use versus drug therapy
Polycystic ovary syndrome diagnosis is associated with increased risk of preterm delivery in twin pregnancies

PCOS Linked to Increased Risk of Preterm Delivery for Twins

Risk particularly increased for spontaneous preterm delivery, very preterm birth
In a review article published online Sept. 3 in the New England Journal of Medicine

Suggested Response Provided for In-Flight Medical Emergencies

Article offers tips for physicians providing emergency in-flight medical care
For patients with type 2 diabetes

Modest Relation Between HbA1c, Cardiovascular Events

No statistically significant interaction for difference seen for those with, without vascular disease
Consumption of sugar-sweetened beverages by children is positively associated with triglyceride concentration

Sugary Beverage Intake Linked to Triglycerides in Children

Reduction in sugar-sweetened beverage intake over 12 months linked to increase in plasma HDL
Patients with chronic myeloid leukemia who received a glitazone along with imatinib remained disease-free for up to nearly five years in a study published online Sept. 2 in Nature.

Addition of Glitazone to Chemo May Help Treat CML

Combining glitazones with standard treatment improved survival in small study
Individuals with type 2 diabetes mellitus may be more prone to developing the neuropathology associated with Alzheimer's disease

Type 2 Diabetes Linked to More Alzheimer’s Neuropathology

Effect may be driven by tau phosphorylation, researchers say
For patients with diabetic nephropathy receiving an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker

Finerenone Linked to Improved UACR in Diabetic Nephropathy

Addition of finerenone to ACE inhibitor or ARB tied to reduction in urinary albumin-creatinine ratio