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An adjunctive buprenorphine/samidorphan combination seems beneficial for patients with major depressive disorder with inadequate response to antidepressant therapy

Buprenorphine/Samidorphan Helpful in Refractory Depression

Consistently greater reduction in MADRS score from baseline seen for BUP/SAM versus placebo
Stratifying tuberculosis patients by disease severity may enable shorter treatment regimens

Stratifying by Severity May Allow Shorter TB Tx Regimens

Those with minimal disease may be cured with a four-month versus six-month treatment regimen
Following the 2007 American Heart Association update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE)

AHA: After 2007 Recs, Increase Seen in Infective Endocarditis

Twenty percent drop in antibiotic prophylaxis, 177 percent increase in IE incidence for high-risk
It may not be possible to bring the Ebola outbreak in Congo under control

CDC Director Says Congo Ebola Outbreak May Be Uncontainable

Outbreak in North Kivu province is in its fourth month, and there have been nearly 300 cases
Prenatal exposure to most medications affecting neurotransmitter systems is not associated with estimates of autism spectrum disorder risk

Most Meds Affecting Neurotransmitters Not Linked to Autism Risk

Prenatal exposure to 5 groups of meds had nominally significant links to ASD
Opioid use is associated with the risk for developing atrial fibrillation

AHA: Opioid Use Appears to Up Risk for Atrial Fibrillation

Opioid prescription independently tied to likelihood of having atrial fibrillation in cohort of young veterans
A majority of internists still report financial ties to industry

Majority of Internists Still Have Financial Ties to Industry

Most common benefits received were drug samples and food and beverage
The number of opioid overdose deaths in the United States reached a new record last year with 72

U.S. Opioid Overdose Deaths Reach Record Number

Heroin, fentanyl, and other opioids continue to be the highest drug threat in the nation
Ruling against the recommendation of one of its chief experts

FDA Approves Powerful New Opioid Despite Criticisms

Dsuvia use restricted to operating rooms or on the battlefield
Almost half of parents report saving leftover antibiotics

AAP: Parents Frequently Save Leftover Antibiotics

Almost three-quarters of those saving antibiotics subsequently divert the antibiotics to others