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Discontinuing tumor necrosis factor inhibitors before gestational week 20 in women with well-controlled rheumatoid arthritis or juvenile idiopathic arthritis is not associated with disease worsening in late pregnancy

Discontinuing TNFi Before Gestational Week 20 Is Feasible

No clinically meaningful disease worsening among women with well-controlled RA, juvenile arthritis
Improving clinic capacity to respond to patients' social needs may reduce primary care physician burnout

Physician Burnout Tied to Ability to Address Social Needs

Risk for burnout lower in clinics with social worker, pharmacist on care team
A shortage of the anti-anxiety drug buspirone in the United States has patients and doctors concerned.

Shortage of Anxiety Drug Creates Alarm Among Patients, Doctors

Buspirone price has fallen so low that many manufacturers claim they cannot make a profit on it
Electronic cigarettes are more effective for smoking cessation than nicotine replacement therapy

E-Cigarettes More Effective for Smoking Cessation

One-year abstinence higher with e-cigarettes than other nicotine replacement products
Switching from analogue to human insulin is associated with a small increase in hemoglobin A1c levels

Small Increase in HbA1c Seen With Switch to Human Insulin in T2DM

No increase in serious hypoglycemia, hyperglycemia after switch from analogue to human insulin
The first generic form of the Advair Diskus (fluticasone propionate and salmeterol inhalation powder) inhaler has been approved by the U.S. Food and Drug Administration.

FDA Approves First Generic Version of Advair for Asthma, COPD

Medication approved to treat children aged 4 or older with asthma, adults with asthma or COPD
For patients being treated for bone or joint infection

Oral Antibiotics Noninferior to IV for Bone, Joint Infection

Noninferiority in intention-to-treat analysis; supported by complete-case, per-protocol, sensitivity analysis
It is important to discuss family planning and pregnancy proactively in women of childbearing age who have multiple sclerosis

Management of MS in Pregnancy Reviewed in U.K. Guideline

Pros and cons of continuing treatment throughout pregnancy should be discussed individually
Methotrexate is well tolerated and effective for psoriasis in a Chinese population and is more effective for those without psoriatic arthritis

Methotrexate Well Tolerated, Effective for Psoriasis in Chinese

Greater therapeutic response, fewer adverse events seen in those without psoriatic arthritis
The compendia used by Medicare for making coverage determinations are inadequate for dermatologic illnesses

Off-Label Uses in Dermatology Often Missing From Compendia

Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia