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Dietary Supplement Use Not Linked to Mortality Benefits

Excess calcium intake may increase risk for cancer death; link related to supplemental calcium intake
Preventive drugs are frequently used in the last year of life among older adults with cancer

Preventive Drugs Often Used in Last Year of a Cancer Patient’s Life

Preventive drugs, including antihypertensives and statins, frequently continued until final month of life
A post hoc analysis of data from a randomized trial shows no difference between older and younger patients for the safety and efficacy of early combined immunosuppression therapy compared with conventional management for Crohn disease

Older Patients With Crohn Disease May Benefit From Early Combo Tx

Early step-up combo therapy includes tumor necrosis factor-α antagonist plus an antimetabolite
For children with acute respiratory infections

Telemedicine Leads to More Antibiotic Rx for Pediatric Respiratory Infection

More antibiotics prescribed with less guideline-concordant antibiotic management versus other settings
The U.S. Food and Drug Administration is warning patients not to use preowned test strips or test strips not authorized for sale in the United States because of possible infection or inaccurate results that could cause serious harm.

FDA Warns Against Use of Preowned or Unauthorized Test Strips

Unauthorized, preowned test strips could cause infection, inaccuracy
The U.S. Food and Drug Administration has announced the approval of Dovato (dolutegravir and lamivudine)

First Two-Drug Regimen Approved for HIV-1 Treatment

Dovato indicated for use in patients with no history of antiretroviral treatment
Higher levels of dietary and supplementary calcium intake appear to be associated with a lower incidence of progression to late age-related macular degeneration

Calcium Intake Tied to Lower Rate of Late AMD

Patients encouraged to continue taking calcium if needed for other indications
In patients with myalgic encephalomyelitis/chronic fatigue syndrome

No Benefit Seen With Rituximab for Chronic Fatigue Syndrome

B-cell depletion using several rituximab infusions over 12 months not linked to clinical improvement
There is a positive association between use of topical corticosteroids and incident type 2 diabetes

Topical Corticosteroids Associated With Higher Risk for Type 2 Diabetes

Dose-response relationship observed in large European cohort
For women with cervical intraepithelial neoplasia grade 2 or 3 associated with high-risk human papillomavirus

Histologic Clearance of CIN2/3 Seen With HPV Therapeutic Vaccine

In phase II trial, rate of complete resolution of CIN2/3 significantly higher for vaccine versus placebo group