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A case report published online Jan. 4 in JAMA Neurology highlights a neuropsychological test profile conducted on a patient with chronic traumatic encephalopathy.

Signs of CTE in Brain of Deceased 25-Year-Old Football Player

Neuropsychological profile conducted prior to death of patient who had played football from age 6
Initial diagnostic characteristics may be able to identify men initiating active surveillance who could avoid confirmatory biopsy

Diagnostic Factors May Help Patients Avoid Prostate Biopsy

Prostate-specific antigen density, total tumor length are significant predictors
β-genus human papillomavirus is a risk factor for cutaneous squamous cell carcinoma in otherwise healthy individuals

β-Genus Human Papillomavirus Poses Skin Cancer Risk

HPV subtypes 5, 8, 17, 20, and 38 tied to significant increased risk
For patients with non-small-cell lung cancer with activating epidermal growth factor receptor mutations

Support for First-Line Erlotinib in NSCLC With EGFR Mutations

And erlotinib therapy beyond progression may delay salvage tx for some patients

December 2015 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for December 2015. This roundup includes the latest...
Third-trimester screening for alloimmunization in Rhesus c-negative women improves detection and treatment of hemolytic disease of the fetus and newborn

Third-Trimester Screen Detects Late Alloimmunization

Detection through additional screening facilitates timely treatment
Higher secretion rates of secretory immunoglobulin A are associated with decreased risk of cancer death

Secretory IgA Secretion Rate Linked to Risk of Cancer Death

Lower risk of non-lung cancer deaths observed with increased sIgA secretion rate
For patients receiving antimicrobial injections targeting methicillin-resistant Staphylococcus aureus

Antimicrobial Stewardship Improves Outcomes for MRSA

Daily review of prescriptions linked to reduction in time to administer effective antimicrobials
Physician burnout is the top issue for physicians in 2015

AMA: Burnout Is Top Issue for Physicians in 2015

More than half of docs report at least one symptom of burnout; efforts being undertaken to address burnout
Chronic drinking combined with binge drinking may be more destructive than previously thought

Alcohol Binge Damage May Be Worse Than Previously Thought

Per experimental study of chronic alcohol use combined with frequent binges