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The Runt-related transcription factor 1 gene may play a role in human proliferative diabetic retinopathy

RUNX1 May Play Role in Proliferative Diabetic Retinopathy

RUNX1 upregulated in CD31+ vascular endothelial cells from human PDR fibrovascular membranes
Kidney disease is a major cause of cardiovascular deaths worldwide

Reduced Glomerular Filtration Rate Major Cause of CV Deaths

Finding points to need for screening for kidney function
Breast cancer rates among Asian-Americans are steadily rising in contrast to other racial/ethnic groups

Breast Cancer Rates Increasing Among Asian-American Women

Out of 7 nationality groups studied, only Japanese women didn't have an overall increase in the disease
Despite guidelines

24-Hour Urine Collection of Unclear Benefit in Stone Formers

Findings among studies predicting kidney stone recurrence or treatment response
Women with newly-developed depression before a breast cancer diagnosis have a modestly

Mortality Up With Depression Just Before Breast Cancer Diagnosis

Newly-developed depression before diagnosis linked to higher risk of death in postmenopausal women
Close to half of breast cancer patients who choose to have a double mastectomy after genetic testing may not have the gene mutations known to raise the risk of additional cancers

Misunderstanding of BRCA Test Results Affects Mastectomy Rates

Half of average-risk patients with variants of uncertain significance may undergo bilateral mastectomy
The incidence of diabetes is increasing among young persons

Diabetes Continues to Be a Significant Public Health Burden

But progress seen in cardiovascular complications, mortality among these patients
An accurate diagnosis of endocrine hypertension allows clinicians to provide effective treatment

Accurate Diagnosis of Endocrine Hypertension Important

Accurate diagnosis allows clinicians to provide surgical cure, achieve optimal response to drugs
Cancer rates differ between African- and U.S.-born black Americans

Cancer Occurrence Differs Among African-Born, U.S.-Born Blacks

Research suggests differences in environmental, cultural, social, genetic factors
There is a low risk of development of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett's esophagus of <1 cm (irregular Z line) within five years of index endoscopy

Barrett’s With Irregular Z Line Unlikely to Progress Quickly

Within five years, incident cancer cases observed only in patients with Barrett's esophagus ≥1 cm