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Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death

Odds of Death Up With Exposure to Pregabalin, Opioids

Dose-response association with highest odds of opioid-related death with high-dose pregabalin
First-year residents experience worsening sleep duration and quality as well as daytime sleepiness

Residents’ Sleep Deteriorates During Training

Worsening seen for sleep duration, quality of sleep, and daytime sleepiness
Pediatric patients with chronic kidney disease have higher global cerebral blood flow and regional differences in cerebral blood flow

Cerebral Blood Flow Changes in Pediatric Patients With CKD

Pediatric patients with CKD showed higher global CBF attributed to reduced hematocrit level
Administering the Visual Association Test improves the predictive value of the Mini-Mental State Examination score for dementia

VAT Score Improves Predictive Value of MMSE for Dementia

Imperfect VAT score plus decline in MMSE score over two years helps identify those at higher risk
A U.S. National Institutes of Health oversight panel will no longer review all applications for gene therapy experiments. Instead

Comments Open on End of NIH Review for Gene Therapy Studies

NIH oversight panel no longer plans to review all applications for gene therapy experiments
A brain stimulation device to treat obsessive-compulsive disorder has received approval for marketing by the U.S. Food and Drug Administration.

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines
Certain steps should be taken when discharging a patient for failure or inability to meet financial obligations

Steps Provided for Discharging Patient From Practice

Letter should be sent informing patient of their discharge, providing at least 30 days' notice
Patient portals have not taken off as expected

Patient Portals Don’t Appear to Have Much Traction

Patients not accessing them, physicians not using full range of features
Opioid dependence is more likely to occur in patients with degenerative spondylolisthesis before surgery than afterward

Opioid Dependence More Common Before Spine Surgery

Findings based on large study of patients having surgery for degenerative spondylolisthesis
After the expanded coverage provisions of the Affordable Care Act were implemented in 2014

ACA Coverage Gains Include Workers Without Insurance

Reduction in uninsurance rate among this group larger than that of not-employed adults