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Its extremely high price tag means that a lifesaving medication to treat young children with spinal muscular atrophy is simply too expensive for most families.

Lifesaving Drug for Infants Costs $2.1 Million a Dose

When Zolgensma was approved, maker Novartis said it expected insurance companies to cover the cost
Intensive blood pressure lowering nonsignificantly reduces the risk for recurrence among patients with a history of stroke compared with a standard blood pressure-lowering regimen

Authors Say Lower BP Targets May Cut Recurrent Stroke Risk

Data from randomized trial with nonsignificant findings added to updated meta-analysis
For aging men with low testosterone levels

Testosterone Replacement Therapy May Increase Cardiovascular Risk

Increased risk in men on TRT for composite of heart attack, ischemic stroke, transient ischemic attack
Physical examination signs are not sufficiently sensitive for detecting elevated intracranial pressure in critically ill adults

Review Examines Methods for Diagnosis of Elevated ICP in Critically Ill

Physical examination features not sensitive enough for diagnosis of elevated ICP in critically ill patients
Metformin use is associated with a substantially lower risk for dementia among younger African-American patients with diabetes compared with sulfonylurea initiation

Metformin May Lower Dementia Risk in Black Patients With T2DM

Findings strongest in younger African-American patients aged 50 to 64 years
Age-adjusted death rates decreased for Hispanic adults from 2000 through 2017

CDC: Mortality Rates Continue to Decrease for Hispanic Adults

Difference in death rates between non-Hispanic white, Hispanic adults widened from 2000 to 2017
A warning letter has been issued to Massachusetts-based Curaleaf Inc. for illegally selling unapproved cannabidiol products online with unproven claims that the products treat cancer

FDA Warns CBD Product Maker About False Claims

Agency says unproven claims about CBD products could lead consumers to delay medical care
Adiposity in early old age is associated with reduced gray matter later in life

Adiposity in Early Old Age Tied to MRI Signs of Brain Aging Later

Higher BMI, larger waist circumference in one's 60s significantly associated with cortical thinning
For youth with attention-deficit/hyperactivity disorder

Stimulant Treatment Has Strong Protective Effect in ADHD

Number needed to treat was low and varied from three to 10 for youth with ADHD
Shorter time to endovascular-reperfusion therapy is associated with improved outcomes among patients with acute ischemic stroke due to large vessel occlusion

Initiating Stroke Tx 15 Minutes Earlier Can Improve Outcomes

Findings seen in patients with acute ischemic stroke treated with endovascular-reperfusion therapy