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Genetics could play a role in the development of melanoma even for skin without extensive sun exposure

MC1R Variants May Up Melanoma Risk, Even Without Sun Exposure

Variant of gene linked to skin pigmentation tied to higher risk
The U.S. Food and Drug Administration has approved its second-ever "biosimilar" drug

FDA Approves Inflectra as ‘Biosimilar’ to Remicade

For adults with Crohn's, rheumatoid arthritis, or psoriasis
Regular doses of vitamin D3 may improve cardiac function in heart failure patients

ACC: Vitamin D Found to Improve Cardiac Function in Heart Failure

Further studies necessary to determine whether this translates to improvements in outcomes

The Endocrine Society, April 1-4

The Endocrine Society's 98th Annual Meeting & Expo The annual meeting of The Endocrine Society (ENDO 2016) was held from April 1 to...
Sleep deprivation does not exacerbate cognitive impairment induced by hypoglycemia

Hypoglycemia, Sleep Loss Prolong Cognitive Impairment

Sleep deprivation does not worsen impairment in type 1 diabetes, but recovery takes longer
For patients with acute liver failure

Recent Improvement in Survival for Acute Liver Failure

From 1998 to 2013, improvement in overall, transplant-free survival in patients with ALF
For companies providing virtual visits for management of common acute illness there is significant variation in quality of care

Quality of Urgent Health Care Varies for Virtual Visits

For six common acute illnesses, significant variation seen across companies and by condition
For patients with new-onset postoperative atrial fibrillation

ACC: Rate, Rhythm Control Both Effective for Post-Op A-Fib

Equal number of days of hospitalization, similar complication and persistent a-fib rates
Early intravenous metoprolol before primary percutaneous coronary intervention does not reduce infarct size in a population with ST-segment elevation myocardial infarction

ACC: Pre-pPCI Metoprolol Doesn’t Reduce Infarct Size in STEMI

Metoprolol cut incidence of malignant arrhythmias; was not linked to increase in adverse events
Familial hypercholesterolemia mutations are seen in less than 2 percent of individuals with low-density lipoprotein cholesterol ≥190 mg/dL

ACC: Prevalence of Familial Hypercholesterolemia <2 Percent

For any given observed LDL cholesterol level, increased risk for CAD for FH mutation carriers