Tag: Genetics
Methylation of Gene Panel May Help Predict Breast CA Survival
High cumulative methylation index linked to shorter median progression-free, overall survival
Intermittent Hypoxia Promotes Lung Tumor Cell Aggressiveness
IH-induced exosomes from mice significantly promote TC1 malignant properties
Updated Index Predicts Survival in NSCLC With Brain Metastases
Significant prognostic factors include four factors from earlier index, plus EGFR and ALK alterations
Guidelines Developed for HER2 Testing in Gastroesophageal CA
Tumor specimens should be assessed for HER2 status before initiation of HER2-targeted therapy
Genetic Mortality Risk Can Be Attenuated by Lifestyle
Mortality up to 64 percent lower for those with low-risk lifestyle profile, independent of genetic risk
BACH2 Identified As Risk Locus for Addison’s Disease
Extended exome capture array shows BACH2 correlates with Addison's disease development
Smoking Ups Cancer Risk by Causing Distinct Cell Mutations
For every year of smoking a pack daily, 150 more mutations found in each lung cell
Genetic Testing May Help ID VTE Risk in Breast Cancer Patients
Older breast cancer patients with increased genetic susceptibility receiving chemo have highest risk
Gene Tx Promising in Recessive Dystrophic Epidermolysis Bullosa
Grafts of patients' genetically modified skin improved healing of wounds in early study
Men With Genetic Risk of CRC May Lower Risk Via Healthy Lifestyle
Adopting healthy lifestyle can cut 25-year risk for the disease from 29 to 13 percent