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Mifepristone pretreatment improves medical management of early pregnancy loss

Mifepristone Pre-Tx Improves Management of Early Miscarriage

Successful management likely for pretreatment with mifepristone followed by misoprostol
A recall of the opioid overdose antidote Naloxone was announced Monday. The U.S. Food and Drug Administration said the recall was triggered by the possibility of "loose particulate matter on the syringe plunger" that could pose a number of health risks

FDA: Opioid Antidote Naloxone Recalled

Two lots of Naloxone recalled due to potential presence of particulate matter in syringe plunger
For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer

ASCO: Pembrolizumab Superior for Initial Tx of Advanced NSCLC

Improved overall survival versus chemotherapy regardless of the PD-L1 tumor proportion score
For patients with metastatic renal cell carcinoma classified as having intermediate or poor prognostic risk

ASCO: Sunitinib Alone Noninferior in Metastatic Renal Cell Cancer

Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival
The safety profile of oral propranolol seems to be good for children with infantile hemangioma

Oral Propranolol Seems Safe for Infantile Hemangioma

Good safety profile for children with infantile hemangioma with no prespecified underlying disease
For patients with episodic migraine

Galcanezumab Beats Placebo for Episodic Migraine

Treatment with 120- or 240-mg galcanezumab linked to reduction in migraine days versus placebo
The safety profile of oral propranolol seems to be good for children with infantile hemangioma

Oral Propranolol Seems Safe for Infantile Hemangioma

Good safety profile for children with infantile hemangioma with no prespecified underlying disease
For patients with episodic migraine

Galcanezumab Beats Placebo for Episodic Migraine

Treatment with 120- or 240-mg galcanezumab linked to reduction in migraine days versus placebo
Most patients are newly initiated on antidiabetic therapy or have antidiabetic therapy intensified within six months of hemoglobin A1c elevation

Elevated HbA1c Usually Leads to Prompt Tx Start, Intensification

Within 6 months of elevated HbA1c, rate of initiation 63 percent, rate of intensification 82 percent
Twice-weekly certolizumab biologic appears to be both safe and effective for the treatment of moderate-to-severe chronic plaque psoriasis

Certolizumab Looks Promising for Moderate-to-Severe Psoriasis

Higher-dose certolizumab (400 mg) better at cutting symptoms than low-dose (200 mg)