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For patients with metastatic renal cell carcinoma classified as having intermediate or poor prognostic risk

ASCO: Sunitinib Alone Noninferior in Metastatic Renal Cell Cancer

Sunitinib alone noninferior to nephrectomy plus sunitinib with respect to overall survival
The safety profile of oral propranolol seems to be good for children with infantile hemangioma

Oral Propranolol Seems Safe for Infantile Hemangioma

Good safety profile for children with infantile hemangioma with no prespecified underlying disease
For patients with episodic migraine

Galcanezumab Beats Placebo for Episodic Migraine

Treatment with 120- or 240-mg galcanezumab linked to reduction in migraine days versus placebo
The safety profile of oral propranolol seems to be good for children with infantile hemangioma

Oral Propranolol Seems Safe for Infantile Hemangioma

Good safety profile for children with infantile hemangioma with no prespecified underlying disease
For patients with episodic migraine

Galcanezumab Beats Placebo for Episodic Migraine

Treatment with 120- or 240-mg galcanezumab linked to reduction in migraine days versus placebo
Most patients are newly initiated on antidiabetic therapy or have antidiabetic therapy intensified within six months of hemoglobin A1c elevation

Elevated HbA1c Usually Leads to Prompt Tx Start, Intensification

Within 6 months of elevated HbA1c, rate of initiation 63 percent, rate of intensification 82 percent
Twice-weekly certolizumab biologic appears to be both safe and effective for the treatment of moderate-to-severe chronic plaque psoriasis

Certolizumab Looks Promising for Moderate-to-Severe Psoriasis

Higher-dose certolizumab (400 mg) better at cutting symptoms than low-dose (200 mg)
The 2017 American College of Cardiology/American Heart Association hypertension guideline is associated with an increase in the proportion of adults recommended for antihypertensive treatment compared with the 2014 guideline

Increase in Tx Candidates With 2017 Hypertension Guidelines

Increase in proportion of adults recommended for treatment; estimated decrease in CVD events, deaths
Add-on dupilumab reduces the rate of severe asthma exacerbations in uncontrolled asthma; it also reduces the glucocorticoid dose for glucocorticoid-treated asthma

Dupilumab Reduces Rate of Severe Asthma Exacerbations

And, add-on dupilumab reduces glucocorticoid dose in patients with glucocorticoid-treated asthma
Offspring born to mothers with rheumatoid arthritis who are exposed to tumor necrosis factor α inhibitors in the gestational period do not have a significantly increased risk of serious infections

TNFi Exposure In Utero Does Not Up Serious Infection Risk

No increased risk of serious infection among RA offspring versus non-TNFi exposed or control