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A case of simultaneous diagnosis of systemic lupus erythematous (SLE) and pheochromocytoma

Simultaneous Diagnosis of SLE, Pheochromocytoma Described

Systemic lupus erythematous disappeared after treatment of concomitant pheochromocytoma
Neither the American College of Rheumatology nor the Systemic Lupus International Collaborating Clinics criteria distinguishes
patients with subacute cutaneous lupus erythematosus with major internal disease from those without

SLICC/ACR Criteria Don’t ID Severe Internal Disease in SCLE

Clinicians should not rely on these criteria in subacute cutaneous lupus erythematosus
Scientists have gained new insight into systemic lupus erythematosus which they hope will lead to new therapies

Research Offers Clues to Impact of Lupus on Immune System

Regulatory B cells becoming pro-inflammatory instead of protective
Blood tests may help identify women with systemic lupus erythematosus who are at high risk for complications during pregnancy

Biomarkers Help ID Complications in Pregnant Women With Lupus

As early as 12 weeks, could signal danger of complications for both mother and infant
Metabolic syndrome is common in young

Metabolic Syndrome Common in Young Women With Lupus

Antimalarial protects against metabolic syndrome, countering steroid effects
For patients with systemic lupus erythematosus

Vitamin D Shows No Impact on Interferon Response in SLE

No change in interferon signature in vitamin D-deficient patients, those with vitamin D repletion
When systemic lupus erythematosus is under control

Pregnancy Outcomes Good for Women With Controlled SLE

Blacks, Hispanics face greater odds of complications; reasons why are unclear
About 8 percent of patients with systemic lupus erythematosus have pulmonary hypertension

About 8 Percent of SLE Patients Have Pulmonary HTN

Patients have few cardiopulmonary symptoms; serum uric acid can predict presence of PH
Fc gamma receptor 3B (FCGR3B) copy number loss is associated with increased risk of systemic lupus erythematosus and lupus nephritis

FCGR3B Copy Number Loss Ups SLE, Lupus Nephritis Risk

Increased risk of systemic lupus erythematosus, lupus nephritis with copy number loss, not gain
Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis

Proteinuria Level Predicts Renal Outcome in Lupus Nephritis

Urinary red blood cells undermine a composite prediction of renal outcome