Tag: Genetics
Meta-Analysis: ABCG2 Q141K Polymorphism Tied to Gout Risk
T allele linked to increased gout risk; association affected by gender, ethnicity
Model Including CRC Risk Alleles Ups Risk Discrimination
Model more accurately determines risk of colorectal cancer; defines recommended screening age
ASCO: MMR Deficiency Predicts Pembrolizumab Response
Findings may help doctors better choose patients to receive pembrolizumab (Keytruda)
Genetic Variants Linked to Educational Attainment
CNVs linked to lower education attainment in geographically distinct unselected populations
ASCO: Many Cancer Patients Interested in Genetic Profiling
Two-thirds of patients feel that tumor profiling could improve their treatment; many will pay out of pocket
Resistance Training Effects Vary Per Genetic Profiles
Not as effective in women with high risk for obesity
X-Linked TEX11 Mutations Identified in Azoospermia
Mutations in TEX11 occur in some men with azoospermia with meiotic arrest
Some Gene Activity Differs Depending on Season
Altered activity could explain why some diseases are worse in some months than others
PTSD Associated With Premature Senescence
Evidence of reduced leukocyte telomere length, increased pro-inflammatory markers
Next-Generation Sequencing Panel Cost-Effective for CRC
Panel including genes linked to highly penetrant CRC and polyposis syndromes seems cost-effective
