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Tag: Diabetes: Type II

Liraglutide added to capped insulin is associated with reductions in glycated hemoglobin

Liraglutide Added to Capped Insulin Reduces Hemoglobin A1c

Liraglutide also significantly reduces mean body weight, daily insulin dose; increases quality of life
The interaction between the organic cation transporter 1 and the serotonin reuptake transporter seems to play a role in metformin intolerance

OCT1, SERT Genes Play Role in Metformin Intolerance

Intolerance up with low-expressing SERT S* alleles; multiplicative interaction for OCT1, SERT genotypes
Twenty-four weeks of empagliflozin + metformin correlates with a significantly greater reduction in hemoglobin A1c compared with once-daily empagliflozin or twice-daily metformin

Greater Drop in Hemoglobin A1c With Empagliflozin + Metformin

Greater reductions in HbA1c, weight compared to empagliflozin or metformin alone
A collaborative couples telephonic intervention is associated with significant improvement in hemoglobin A1c levels

Couple Phone Intervention Ups Glycemic Control for High A1C

No difference for phone (individual, couple), education interventions at highest A1C levels
Routinely measured lipid fractions may be associated with the risk of coronary artery disease and diabetes

Lipid Fractions May Be Linked to Risk of CAD, Diabetes

Increase in LDL-C, triglycerides linked to higher CAD risk; LDL-C, HDL-C linked to lower risk of diabetes
For insulin-resistant patients with recent ischemic stroke or transient ischemic attack

Pioglitazone Cuts Diabetes Risk After Ischemic Stroke, TIA

Findings for patients with recent ischemic stroke/TIA and insulin resistance, but no history of diabetes
Patients with nonfunctional adrenal tumors have increased risk of diabetes compared to those without adrenal tumors

Increased Risk of Diabetes With Nonfunctional Adrenal Tumors

Increased risk of incident composite diabetes compared to those without adrenal tumors
Patients with impaired glucose tolerance face an increased risk of mortality

Mortality Up With Impaired Glucose Tolerance

Much of the increase associated with impaired glucose tolerance due to progression to diabetes
After adjustment for confounding variables

No Independent Link for Fatty Pancreas, T2DM

After adjustment for confounding variables, no significant correlation remains
Secreted frizzled-related protein 4 is associated with impaired glucose tolerance and type 2 diabetes

SFRP4 Linked to Impaired Glucose Tolerance, T2DM

Higher levels of secreted frizzled-related protein 4 associated with impaired glucose tolerance, T2DM