Advertisement
Home Tags Cancer: Colon

Tag: Cancer: Colon

Insurance coverage differences account for about half of the disparity in survival rates between black and white patients aged 18 to 64 years with colorectal cancer

Insurance Underlies Black-White Survival Disparity in CRC

54 percent of excess risk of death in black colorectal cancer patients accounted for by insurance matching
Fewer than half of younger adults with colorectal cancer undergo mismatch repair deficiency of DNA testing

Use of MMR Deficiency Testing in Younger CRC Patients Is Low

Just 43.1 percent underwent mismatch repair deficiency of DNA testing
Higher fiber intake after a diagnosis of nonmetastatic colorectal cancer (CRC) is associated with lower CRC-specific and overall mortality

Fiber Tied to Lower Mortality in Those With Colorectal Cancer

Increasing fiber consumption after diagnosis may lower risk of all-cause, CRC-specific mortality
After adoption of the Affordable Care Act

Incidence of Early-Stage Breast CA, CRC Up With ACA Adoption

No change in incidence of locally advanced or metastatic-stage cancer after ACA adoption
A significant increase in colorectal lesion frequency is seen at 45 years of age

Colorectal Lesion Frequency Increases at Age 45

Polyp, adenoma, and neoplasia detection rate higher in 45-49 age group than in younger patients
Higher HER3 expression is associated with improved survival with the addition of panitumumab treatment for patients with RAS wild-type advanced colorectal cancer

HER3 Linked to Improved Survival With Panitumumab

Addition of panitumumab to irinotecan tied to improved survival in RAS wt advanced colorectal CA
For patients undergoing left colon and rectal cancer resections

Oral Antibiotics Cut Risk of SSI in Colorectal CA Resection

Adding antibiotics to mechanical bowel preparation linked to reduced rate of surgical site infection
Adding surveillance to fecal immunochemical test screening reduces colorectal cancer mortality and increases colonoscopy demand

Adding Surveillance to FIT Screening Cuts CRC Mortality

But addition of surveillance is not cost-effective based on Dutch incremental cost-effectiveness ratio
Administration of histamine-producing gut microbes to histidine decarboxylase-deficient mice reduces inflammation and tumor formation

Histamine May Play Role in Colorectal Tumorigenesis

Histamine-producing probiotic reduces inflammation, suppresses colon tumors in mice
Monthly feedback significantly improves colonoscopy quality measures

Monthly Feedback Linked to Improved Colonoscopy Quality

But no improvement observed with quarterly feedback