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Monthly Archives: February 2019

There is seasonal variation in achievement of the guideline targets for hemoglobin A1c

Achievement of Targets in T2DM Varies by Season

Achievement rates for all three targets and for HbA1c, BP, LDL-C are lowest in the winter
The proportion of human papillomavirus 16/18-positive cervical intraepithelial neoplasia grades 2 to 3 or adenocarcinoma in situ declined from 2008 to 2014

Decline Observed in HPV Type 16/18 Cervical Precancers in U.S.

Greatest declines seen among vaccinated women; decreases also seen in unvaccinated women
For clinical stage I testicular cancer patients

Adjuvant Tx for Early Testicular Cancer Does Not Harm Sperm

Adjuvant tx has no clinically significant long-term effect on total sperm number, concentration
Antenatal corticosteroid therapy is associated with reductions in birth size for infants

Antenatal Corticosteroid Tx Tied to Reduction in Birth Size

Reduction in birth size seen for infants born preterm, near term, or at term with ACT exposure
Living around high levels of green space during childhood is associated with a lower risk for a wide spectrum of psychiatric disorders later in life

Green Space in Childhood Tied to Better Mental Health Later

Authors say findings show importance of integrating natural environments into urban planning
While smoking is a strong risk factor for seropositive rheumatoid arthritis

Sustained Smoking Cessation May Delay, Prevent Seropositive RA

While risk increases with pack-years smoked, it decreases with longer duration of smoking cessation
Fluoroquinolone stewardship interventions at hospitals are associated with less fluoroquinolone prescribing during hospitalization but not at discharge

Stewardship Programs Decrease Inpatient Fluoroquinolone Rx

Interventions tied to less prescribing in hospital but did not impact fluoroquinolone discharge treatment
For patients with advanced Merkel cell carcinoma

Tumor Control Durable With Pembrolizumab in Merkel Cell Cancer

28 of 50 advanced MCC patients responded; 24-month overall survival rate was 68.7 percent
From 2013 to 2017

Rate of Opioid Rx Stable After Pediatric Outpatient Surgery

However, maximum available take-home dose steadily declined from 2013 to 2017
The presence of comorbid chronic kidney disease negatively impacts myocardial revascularization outcomes in patients with type 2 diabetes mellitus

Kidney Disease Affects Revascularization Outcomes

Revascularization patients with T2DM and CKD more likely to experience a major adverse event