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Monthly Archives: February 2019

Omadacycline is noninferior to moxifloxacin for community-acquired bacterial pneumonia and noninferior to linezolid for acute bacterial skin infections

Omadacycline Noninferior to Moxifloxacin for Pneumonia

Second study shows noninferiority to linezolid for acute bacterial skin and skin-structure infections
Federal value-based incentive programs are not associated with reductions in device-associated catheter-associated urinary tract infection rates

Value-Based Incentive Program Does Not Cut Catheter-Linked UTIs

VBIP implementation not linked with immediate changes or changes in trends for any outcome
Irrespective of age and weight

Type 2 Diabetes Risk Up With PCOS Regardless of BMI

PCOS one of most influential predictors of T2DM after adjustment for BMI, education, family history
Implementation of a novel enhanced recovery after surgery protocol can reduce patients' postoperative opioid requirements after elective spinal or peripheral nerve surgery

ERAS Protocol Can Cut Opioid Use After Spine Surgery

Decline seen in postoperative opioid requirements after elective spinal, peripheral nerve surgery
The urban African-American population has a high prevalence of hypertensive crisis and hypertensive emergencies

Hypertensive Crisis Prevalent in Urban African-Americans

Prevalence of hypertensive crisis is 11.4 percent in this population
A magnetic resonance imaging-guided treat-to-target strategy is not associated with improved disease activity remission rates for patients with rheumatoid arthritis in clinical remission

MRI-Guided Tx Strategy Not Superior for Rheumatoid Arthritis

No difference seen in proportion reaching primary end point versus conventional strategy
Treatment of psoriasis with biologic therapy is associated with a reduction in noncalcified coronary plaque and improved plaque morphology

Psoriasis Tx Linked to Drop in Noncalcified Coronary Plaque

Noncalcified plaque burden and necrotic core reduced in association with biologic therapy
Potential antidepressant overprescribing appears to be common among elderly patients and involves mostly newer antidepressants used for nonspecific psychiatric symptoms and subthreshold diagnoses

Antidepressant Overprescribing Appears Common in Elderly

Overprescribing tied to newer antidepressants, non-face-to-face interactions with prescribers
States with above-median OxyContin misuse before reformulation of the drug experienced a 222 percent increase in hepatitis C infection rates after reformulation

Hepatitis C Infection Rates Up After OxyContin Reformulation

222 percent increase in HCV infection rates seen after reformulation in states with above-median misuse
Outcomes are similar for blood type A2 to blood type B and B to B deceased donor kidney transplantation

Blood Type A2 to B Kidney Transplant Feasible

No difference in patient, graft survival; increased costs seen for A2 to B deceased donor kidney transplant