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For patients with hyperthyroidism treated with radioactive iodine

I-131 Tx for Hyperthyroidism May Up Risk for Solid Cancer Death

Greater organ-absorbed doses may be modestly positively associated with risk of solid cancer death
Thyroid hormones are not recommended for adults with subclinical hypothyroidism

Thyroid Hormones Not Endorsed for Subclinical Hypothyroidism

Almost all adults with SCH would not benefit from treatment with thyroid hormones
Complication rates are low following surgery for pediatric thyroid disease at a high-volume center

Complication Rates Low for High-Volume Pediatric Thyroid Surgery

Low complication rates for surgical management of pediatric thyroid disease at high-volume center
For patients with Hashimoto thyroiditis with persistent symptoms despite normal thyroid gland function

Total Thyroidectomy Improves HRQoL in Hashimoto Thyroiditis

Improvement in HRQoL, fatigue for patients with persistent symptoms despite normal thyroid gland function
Readmissions after thyroid surgery are relatively low

Fewer Than 5 Percent of Thyroid Surgery Patients Readmitted

Majority of readmissions occur within seven days of discharge and one-fourth within two days
Thyroid hormone therapy is not associated with improvements in general quality of life or thyroid-related symptoms in non-pregnant adults with subclinical hypothyroidism

Hormone Therapy Not Beneficial in Subclinical Hypothyroidism

No benefit regarding quality of life or thyroid-related symptoms found for thyroid hormone therapy
For patients undergoing thyroidectomy

Thyroidectomy-Specific Quality Improvement Measures ID’d

Hypocalcemia, recurrent laryngeal nerve injury may be useful quality improvement measures
Imaging studies

Ultrasonography Not Necessary for Evaluation of Hypothyroidism

Detection of incidental nodules can lead to further testing, anxiety and may detract from true complaint
There is wide variation in thyroidectomy rates among Medicare beneficiaries nationally

Across U.S., Wide Variation Seen in Thyroidectomy Rates

Rate per 100,000 Medicare beneficiaries ranges from 22 to 139, a 6.2-fold difference
Patients receiving immune checkpoint inhibitor regimens may experience endocrine dysfunction

Immune Checkpoint Inhibitor Endocrine Dysfunction Explored

Patients on combination therapy have increased risk of thyroid dysfunction and hypophysitis