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Home Tags Therapy & Procedures: Misc.

Tag: Therapy & Procedures: Misc.

The first human trial of an antibody therapy to treat COVID-19 is underway

Human Trial of Antibody Therapy to Treat COVID-19 Underway

If drug proves safe and effective, it could be available for use by the fall
Administration of convalescent plasma seems safe and results in improvement in clinical status for patients with severe or life-threatening COVID-19

Convalescent Plasma Appears Promising for Severe COVID-19

In series of 25 patients, 19 experienced improvement in clinical status by day 14; 11 were discharged
Initiation of pulmonary rehabilitation within three months of hospital discharge for chronic obstructive pulmonary disease is significantly associated with a lower risk for mortality at one year for Medicare beneficiaries

Pulmonary Rehab Associated With Lower COPD Mortality

Only 1.5 percent of patients initiated pulmonary rehabilitation within 90 days of discharge
Use of sodium-glucose cotransporter 2 inhibitors is associated with a reduced risk for serious renal events compared with dipeptidyl peptidase-4 inhibitors

SGLT2 Inhibitors Linked to Reduced Risk for Serious Renal Events

Data from three countries showed drop in serious renal events with sodium-glucose cotransporter 2 inhibitors
For adult emergency department patients with syncope

NT-proBNP Does Not Improve Evaluation of Syncope in the ED

Serum NT-proBNP concentrations were generally higher in patients with 30-day serious adverse events
For patients with advanced BRAFV600E/K melanoma

PFS Prolonged With Continuous Dabrafenib, Trametinib in Melanoma

Median PFS longer with continuous versus intermittent treatment, but overall survival similar
The U.S. Preventive Services Task Force concludes that primary care-feasible behavioral interventions have a moderate net benefit for preventing tobacco use in children. These findings form the basis of a final recommendation statement

USPSTF: Behavioral Interventions Likely Prevent Tobacco Use

Primary care-feasible behavioral interventions have moderate net benefit for school-aged children
High-dosage chloroquine diphosphate has potential safety hazards when used as adjunctive therapy for patients hospitalized with severe COVID-19

Adding High-Dose Chloroquine Not Advised for Severe COVID-19

High-dose versus low-dose group had higher lethality until day 13, more instances of QTc interval >500 ms
There is no proven drug treatment for COVID-19 patients

Expert Panel: There Are No Proven Drug Treatments for COVID-19

Whenever possible, drugs should be given to COVID-19 patients as part of a clinical trial
Hydroxychloroquine usage is expanding globally to treat novel coronavirus 2019

Physicians Report Expanding Use of Off-Label COVID-19 Treatments

Hydroxychloroquine usage increasing rapidly, although plasma from recovered patients perceived as more effective