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Systemic Corticosteroids Tied to Vaso-Occlusive Episodes in Sickle Cell

Association seen among children and adults with sickle cell disease; association lower for those exposed to hydroxyurea

Continued Dexamethasone at Discharge Not Tied to Better COVID-19 Outcomes

No association seen with reduced 14-day all-cause readmission or mortality for individuals continuing dexamethasone at discharge

ASN: Steroids Best Placebo in High-Risk IgA Nephropathy

But dose reduced because of increased incidence of serious adverse events with full-dose methylprednisolone

Steroid Injection No Better for Long-Term Carpal Tunnel Symptoms

At five years, no difference seen in symptoms, but rates of subsequent surgical treatment lower with methylprednisolone versus saline injection

Higher Dose of Steroid Does Not Improve Outcomes in Severe COVID-19

Number of days alive without life support at day 28 did not differ with dexamethasone 12 mg versus 6 mg in those with severe hypoxemia

Overweight Children With Asthma Less Likely to Respond to Treatment

Higher body mass index tied to poor response to inhaled corticosteroids

Prophylactic Steroids May Prevent Complications of Thyroidectomy

Rates of postoperative hypocalcemia and voice dysfunction lower with single preoperative dose of dexamethasone versus placebo

Dexamethasone Studied for Treatment of Heavy Menstrual Bleeding

Results of dose-finding study suggest dexamethasone is safe for use at a dosage of 1.8 mg daily for five days per menstrual cycle

Dexamethasone Underused for Adults Hospitalized With COVID-19

Dexamethasone and remdesivir use have gradually increased during the pandemic; hydroxychloroquine use peaked in March 2020

Duration of Maintenance Therapy Studied in Childhood ALL

Vincristine and dexamethasone pulses might be eliminated during second year of treatment for children with low-risk disease