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The synthetic prostaglandin E1 analogue misoprostol has known severe side effects and should be considered in cases of postpartum hyperthermia

Misoprostol Should Be Considered in Postpartum Hyperthermia

Report of 21-year-old with severe hyperthermia, rigors, tachycardia, transient encephalopathy
Anti-programmed cell death-1 therapy for metastatic melanoma is associated with the development of immune-related cutaneous events

Melanoma Therapy Tied to Cutaneous Adverse Events

Anti-programmed cell death-1 therapy tied to lichenoid reactions, eczema, vitiligo
For children with infantile hemangiomas

Serious Propranolol ADRs Rare in Infantile Hemangioma

Most commonly reported adverse drug reactions were respiratory disorders
Dysgraphia after sertraline intake has been documented in a case report published online Jan. 21 in the Journal of Clinical Pharmacy and Therapeutics.

Dysgraphia Described After Sertraline Intake

Case report describes 60-year-old man with tremors and episodes of buccal dyskinesia, dysgraphia
Excessive hair growth can occur after local administration of interferon-β treatment for malignant melanoma

Excessive Hair Growth Documented After IFN-β Tx

Patient received localized IFN-β treatment after resection of malignant melanoma on right thigh
For men with metastatic prostate cancer

More Adverse Effects for Medical Castration in Prostate Cancer

Higher risks of several clinically relevant adverse effects compared with surgical castration
More frequent monitoring may be required when patients are taking both acenocoumarol and levofloxacin due to the possibility of an adverse interaction

Interaction Described Between Acenocoumarol, Levofloxacin

Probable interaction described in five patients, all of whom had atrial fibrillation
Animal studies have uncovered a compound that might reduce the adverse effects of levodopa. The research was published in the Nov. 18 issue of Neuron.

New Compound May Help Reduce Side Effects From Levodopa

Studies in mice, monkeys point to a compound that might lessen levodopa's debilitating effects
Administration of a tamoxifen-phospholipid complex is associated with improvement in tamoxifen-induced hepatotoxicity in rats

Tamoxifen-Phospholipid Complex May Alleviate TMX Toxicity

Rat study demonstrates improvement in tamoxifen-induced hepatotoxicity with TMX-PLC
For women with breast cancer

Hypofractionated Breast Irradiation = Reduced Toxicity

Two studies show benefits for hypofractionated vs conventionally fractionated whole-breast irradiation