Tag: Prescription Drugs
Idalopirdine May Not Improve Cognition in Mild Alzheimer’s
Findings from three randomized trials show no improvement in cognition vs. placebo over 24 weeks
Week’s Worth of HIV Meds in a Single-Dose Capsule Feasible
Oral platform delivers three antiretrovirals for up to seven days after single administration
Fluorouracil Tied to Reduced Surgery for Squamous Cell CA
Reduced risk of squamous cell carcinoma, but not basal cell carcinoma, for one year in at-risk veterans
Esketamine Safe, Effective for Treatment-Resistant Depression
Change in Montgomery-Åsberg Depression Rating Scale score superior for esketamine versus placebo
Immune-Related Adverse Events Up With Checkpoint Inhibitors
Most patients with cancer, autoimmune disease have improvement in events without discontinuing therapy
CVD Risk Up With β2-Agonist, Antimuscarinic Antagonist Start
New use of long-acting β2-agonists, antimuscarinic antagonists tied to higher CVD risk in first 30 days
Predictors of Infliximab Response in Ulcerative Colitis Identified
Baseline Mayo Endoscopic Score, CRP/albumin ratio predict treatment response and risk for colectomy
Few Immuno-Oncology Agents Reach ASCO Efficacy Thresholds
Durable survival, response rates rarely recognized as significant by current oncology value frameworks
Pharmaceutical Aids Not Found to Be Helpful for Smoking Cessation
No evidence that varenicline, bupropion, or nicotine replacement increase probability of abstinence
Increase Seen in Gabapentinoid Use From 2002 to 2015
More than three-fold increase in percentage of adults using gabapentin and/or pregabalin
