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For patients with prostate cancer

ADT May Up Risk for Heart Failure in Prostate Cancer Patients

Heart failure risk higher for androgen deprivation therapy users in propensity score-matched analysis
For patients with primary progressive multiple sclerosis

Ocrelizumab May Help Preserve Hand, Arm Function in PPMS

Ocrelizumab reduces risk for more severe progression
During a median follow-up of 6.8 years

Few Mandatory Pediatric Postmarketing Studies Completed

33.8 percent of mandatory pediatric postmarketing studies completed during 6.8 years of follow-up
A new scoring system that accounts for "not relevant" responses on the Dermatology Life Quality Index for patients with psoriasis is valid for avoiding bias and can improve access to biologics

Novel Scoring System Can Up Access to Biologics in Psoriasis

DLQI-R allows more patients to achieve threshold for becoming candidates for biologic treatment
The risk for sexual transmission of HIV is negligible when an HIV-positive sex partner adheres to antiretroviral therapy and maintains viral suppression

HIV Transmission Risk Small With Antiretroviral Compliance

No transmissions with antiretroviral tx, viral load of less than 200 copies/mL four to six months apart
A patient-centered education bundle intervention can reduce nonadministration of venous thromboembolism prophylaxis

Patient Education Ups VTE Prophylaxis in Hospital Setting

Targeted patient-centered intervention reduces nonadministration of pharmacologic prophylaxis
There are great differences in access to naloxone even among states that have passed legislation to allow pharmacists to dispense the medication without a physician's prescription

Even With Standing Orders, Naloxone Access Varies

Despite standing order legislation in two states, there is great variance in pharmacy availability
Use of sodium glucose cotransporter 2 inhibitors is associated with an increased risk for lower-limb amputation and diabetic ketoacidosis compared with use of glucagon-like peptide 1 receptor agonists

Higher Risk for Amputation, DKA With SGLT2 Inhibitors for T2DM

Risk increased for lower-limb amputation, diabetic ketoacidosis compared with GLP1 receptor agonists
In a simulation of children with peanut allergy

Epinephrine Personal Autoinjectors Cost-Effective at $24

Based on 10-fold fatality risk difference, value-based price for personal epinephrine $24
Combined treatment with glecaprevir and pibrentasvir is highly effective in treating chronic hepatitis C virus genotype-1 infections that failed to respond to direct-acting antiviral therapy

Option Found for Retreatment of Chronic Hep C Infection

Glecaprevir + pibrentasvir effective for those who previously failed direct-acting antiviral treatment