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For patients with cystic fibrosis

Key Cystic Fibrosis Pathogens Reduced With Ivacaftor Use

Ivacaftor use linked to reductions in P. aeruginosa rates, prevalence of S. aureus, Aspergillus species
Since initiation of the iPLEDGE program in 2006 to reduce fetal exposure to isotretinoin

Pregnancies in Women Taking Isotretinoin Dropped Since 2006

Pregnancies reduced in women taking isotretinoin since iPLEDGE initiation in 2006, but exposure persists
In patients with membranous nephropathy at high risk for progressive disease

Rituximab Noninferior to Cyclosporine in Membranous Nephropathy

Drug found to be superior in maintaining proteinuria remission for up to 24 months
Patients with autoimmune diseases have an increased risk for being diagnosed with Crohn disease or ulcerative colitis while under treatment with etanercept

Etanercept Tx for Autoimmune Disease May Up Risk for IBD

Findings seen in patients receiving etanercept for other autoimmune diseases
Oliceridine is being proposed as an analgesic option for the relief of moderate to severe acute postoperative pain

Oliceridine Studied for IV Pain Relief After Abdominoplasty

Findings published from phase III trial of patients with moderate-to-severe acute postoperative pain
Compared with placebo

Rimegepant Shows Promise for Relief From Migraine Attacks

Increase seen in percentage of patients free from pain, from their most bothersome symptom at two hours
A plan to let Medicare patients receive rebates that drug companies currently pay to insurers and middlemen has been withdrawn by the Trump administration.

Medicare Drug Rebate Plan Withdrawn by Trump Administration

Rebates would have been paid directly to seniors in Medicare Part D program when they filled their Rx
There has been a recent increase in the awareness and use of HIV preexposure prophylaxis among men who have sex with men

Awareness, Use of PrEP on Rise Among Men Who Have Sex With Men

PrEP awareness increased by 50 percent overall from 2014 to 2017; however, use is still low
Two new research papers

Two Algorithms Can ID Patients at Risk for HIV, PrEP Candidates

Algorithms use data from EHRs to identify candidates for preexposure prophylaxis
Galcanezumab can reduce the frequency of episodic cluster headache attacks

Galcanezumab Can Cut Frequency of Cluster Headache Attacks

Mean reduction in weekly frequency of cluster headache attacks greater with galcanezumab versus placebo