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Macrolide-resistant Mycoplasma pneumoniae has a prevalence of 13.2 percent in a sample of M. pneumoniae-positive specimens from six locations in the United States

Macrolide-Resistant M. pneumoniae in All U.S. Regions

Prevalence of 13.2 percent in sample of 91 M. pneumoniae-positive specimens from six locations
The annual incidence of community-acquired pneumonia requiring hospitalization is 24.8 cases per 10

Considerable Burden for Community-Acquired Pneumonia

Incidence of community-acquired pneumonia requiring hospitalization is highest in elderly
The 13-valent pneumococcal vaccine (PCV-13) is expected to be cost saving compared with PCV7

PCV13 Predicted to Be Cost Saving Versus PCV7

Although 13-valent pneumococcal vaccine is more costly than PCV7, net cost savings expected
Community-acquired pneumonia is associated with increased risk of long-term adverse events

Community-Acquired Pneumonia Confers Long-Term Risk

High risk of long-term adverse events versus general population, irrespective of age
Patients hospitalized with macrolide-resistant Streptococcus pneumoniae pneumonia are not more severely ill and do not have worse outcomes

Macrolide Resistance Doesn’t Impact Pneumonia Outcomes

Patients hospitalized with macrolide-resistant S. pneumoniae not more severely ill at presentation
Treatment of chronic obstructive pulmonary disease with inhaled corticosteroids is associated with increased risk of pneumonia

ATS: Risk of Pneumonia Up With Inhaled Corticosteroids in COPD

Observational studies show reduction in odds of pneumonia-associated, all-cause mortality
The use of dipeptidyl peptidase-4 inhibitors is not associated with an increased risk of hospitalization for community-acquired pneumonia

DPP-4 Inhibitors Not Tied to Pneumonia Hospitalizations

Findings among new users of antidiabetic drugs from 2007 to 2012
For patients with Streptococcus pneumoniae pneumonia

Outcomes No Worse for Macrolide-Resistant Pneumonia

Macrolide-resistance has no effect on outcomes as a function of compliance with current tx guidelines
Interventions can increase blood culture ordering in children hospitalized with community-acquired pneumonia

Interventions Up Blood Culture Ordering in Pediatric Pneumonia

Increase in blood cultures for kids hospitalized with community-acquired pneumonia; no impact on LOS
For emergency department patients with pneumonia

Real-Time Decision Support Tool Aids ER Pneumonia Patients

Post deployment, significantly lower mortality in patients with community-acquired pneumonia