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Tag: Peripheral Artery Disease

Major bleeding occurs in about 4 percent of lower-extremity peripheral vascular intervention procedures

Study Looks at Risk for Bleeding in Percutaneous Tx of PAD

Major bleeding in lower-extremity peripheral vascular interventions tied to higher in-hospital mortality
Heat therapy can improve functional ability and also has the potential to be an effective cardiovascular conditioning tool for people with peripheral arterial disease

Hot Water Therapy Aids Patients With Peripheral Arterial Disease

Small study shows it improves functional ability, has potential for cardiovascular conditioning
A preliminary analysis has revealed a "potentially concerning signal" of increased long-term mortality risk with paclitaxel-coated products indicated for peripheral arterial disease

FDA Issues Update on Mortality Risk With Paclitaxel-Coated Products

Preliminary analyses revealed approximately 50 percent increased risk at five-year follow-up
Exposure to paclitaxel in drug-coated balloons used in procedures for the treatment of symptomatic femoropopliteal peripheral arterial disease is not associated with mortality

Paclitaxel Exposure in Vascular Device Not Linked to Mortality

No deaths thought to be related to use of paclitaxel drug-coated balloons for vascular procedures in PAD
Cigarette smoking is associated with measures of subclinical peripheral artery disease in African-Americans

Smoking Tied to Peripheral Artery Disease in African-Americans

Current smokers had increased risk for measures of subclinical peripheral artery disease
The U.S. Food and Drug Administration alerted health care providers on Thursday that the agency is investigating the use of paclitaxel-coated balloons and paclitaxel-eluting stents to treat peripheral arterial disease in the femoropopliteal artery because of a potentially increased mortality risk in the long term.

FDA Investigating Paclitaxel-Coated Balloons, Paclitaxel-Eluting Stents

Investigation triggered by meta-analysis showing possible increased mortality in PAD patients at 2 years
Appropriate use criteria have been developed for peripheral artery intervention in peripheral artery disease

Appropriate Use Criteria Released for Peripheral Artery Intervention

Guideline-directed medical therapy, lifestyle and risk factor modification are cornerstones of therapy
The U.S. Preventive Services Task Force concludes that there is currently insufficient evidence to assess the benefits and harms of screening for peripheral artery disease with the ankle branchial index in asymptomatic adults. These findings form the basis of a final recommendation statement published in the July 10 issue of the Journal of the American Medical Association.

USPSTF: Evidence Lacking for ABI for PAD Screen in Asymptomatic

No direct evidence, limited indirect evidence for benefits of PAD screening in asymptomatic population
For patients with peripheral artery disease

Exercise Intervention Doesn’t Improve Walking Ability in PAD

Smaller mean change from baseline to follow-up in 6-minute walking distance with exercise intervention
For patients with peripheral arterial disease who are discharged following peripheral arterial revascularization

About One in Six Readmitted Post-Revascularization for PAD

Most common causes of readmission were procedural complications, sepsis, diabetes complications