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Tag: Muscle Problems

Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle

Young Adults With T1DM Show Muscle Metabolic Deficiencies

Lower mitochondrial oxidative capacity in skeletal muscle of physically active young adults with T1DM
Nusinersen is associated with significant and clinically meaningful improvement in motor function among children with later-onset spinal muscular atrophy

Nusinersen Beneficial in Later-Onset Spinal Muscular Atrophy

Significant improvement in motor function compared with sham procedure among children with SMA
The prevalence of work-related musculoskeletal disorders appears to be high for at-risk physicians

Higher Risk of Musculoskeletal Disorders in Some Physicians

Increasing risk for work-related musculoskeletal disorders, particularly in procedural specialists
New classification criteria have been developed for idiopathic inflammatory myopathies

Criteria Developed for Idiopathic Inflammatory Myopathies

Classification criteria developed from rheumatology, dermatology, neurology, pediatric clinic data
Gene replacement therapy is beneficial in spinal muscular atrophy type 1

Gene Replacement Tx Beneficial in Spinal Muscular Atrophy

And nusinersen improves motor-milestone response for infants with spinal muscular atrophy
Higher levels of echo intensity on ultrasound are associated with lower levels of muscle strength and greater frailty in the elderly

Ultrasound Echo Intensity Is Potential Frailty Biomarker

High levels of echo intensity associated with lower muscle strength in the elderly
Ultrasonography findings seem to correlate well with the disease activity of idiopathic inflammatory myopathies

Ultrasound Findings Correlate With Inflammatory Myopathies

While there is not a single ultrasound pattern, findings tied to disease activity
High blood levels of active vitamin D may increase muscle strength

Increased Active Vitamin D May Help Optimize Muscle Strength

Findings for serum 1,25-dihydroxyvitamin D3 (1α,25[OH]2D3)
Patients with sustained or newly developed cancer cachexia at six and 12 months after initial treatment for advanced head and neck squamous cell carcinoma are at higher risk of cancer recurrences

Cancer Cachexia Associated With Poor Outcomes

Findings at six and 12 months after treatment for advanced head and neck cancer
Use of complementary health approaches is significantly higher for U.S. adults with musculoskeletal pain disorders

CDC: Complementary Health Use Up With Musculoskeletal Pain

Over 41 percent of U.S. adults with musculoskeletal pain disorders use complementary health approach