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Tag: Liver Disease: Misc.

Sarcopenia Worsens Liver Transplant Outcomes for Patients With Cirrhosis

Sarcopenia tied to longer intensive care unit stay, more major complications, higher postoperative mortality

Hepatitis C Virus Still Leading Cause of Hepatocellular Cancer in Men

Since 2017, leading cause of HCC is NAFLD among women; increases in ALD- and NAFLD-HCC seen since 2015

Rates of Tx Retention for Rifaximin Low Despite Benefits for Hepatic Encephalopathy

Lower treatment retention rates seen with 30-day, out-of-pocket costs ≥$150

Technical Variant Graft Usage Affects Pediatric Liver Transplant Waitlist Mortality

Higher technical variant graft usage from living or deceased donor linked to lower waitlist mortality in pediatric liver transplant candidates

Recommendations Developed for Management of Acute Liver Failure

Comprehensive testing is essential to elucidate diagnosis and exclude underlying chronic liver disease

Bulevirtide Linked to Decline in Hepatitis D Virus RNA Levels

Normalization of alanine aminotransferase also seen with bulevirtide 2- or 10-mg

Pegozafermin Leads to Improvements in Fibrosis in NASH

Improvements also seen in NASH resolution with pegozafermin 15 or 30 mg weekly, or 44 mg every two weeks

Novel Dialysis Device Safe, Effective for Acute-on-Chronic Liver Failure

No difference seen in 28-day mortality or occurrence of serious adverse events; time to resolution of ACLF significantly faster

Liver Function Tests Can ID Occult Disorders in Systemic Sclerosis

Predictors of abnormal liver function test include elderly onset of SSc, alcoholic drinking, and edematous skin

Advanced Liver Disease Up With Heavy Alcohol Use With, Without Metabolic Syndrome

Absolute change in advanced liver disease highest in heavy alcohol use subgroups with and without MetS