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Tag: Heartburn / GERD / Indigestion

For U.S. adults with gastroesophageal reflux disease

Proton Pump Inhibitors Linked to Increased Risk of MI

No increased risk seen with H2-blockers
Anxiety and depression are linked to increased severity of retrosternal pain and heartburn and reduced quality of life among patients with gastroesophageal reflux disease

Anxiety, Depression Impact Symptoms, QoL in GERD

Increased anxiety, depression linked to increased severity of retrosternal pain and heartburn
For patients with gastroesophageal reflux disease

Review: Radioablation Offers No Benefit for GERD Patients

No improvement in terms of mean time spent with pH less than 4, ability to stop PPIs, HRQoL
Nocturnal gastroesophageal reflux disease appears to be a risk factor for non-infectious rhinitis

Nocturnal GERD Tied to Non-Infectious Rhinitis

Greater number of reflux episodes reported tied to higher risk of non-infectious rhinitis
A monthly educational intervention paired with a web-based quality improvement tool is feasible for increasing the proportion of inappropriate proton pump inhibitor prescriptions discontinued at hospital discharge

Educational Intervention Can Cut Inappropriate PPI Prescriptions

Increase in proportion of PPIs discontinued at hospital discharge after intervention implementation
The first generic version of Nexium (esomeprazole magnesium delayed-release capsules) has been approved by the U.S. Food and Drug Administration to treat gastroesophageal reflux disease in adults and children ages 1 and older.

FDA Approves Generic Form of Nexium

To treat gastroesophageal reflux disease in adults and children ages 1 and older
An electronic alert triggered on order of intravenous (IV) proton pump inhibitors (PPI) can decrease the proportion of IV PPIs ordered

Electronic Alert Cuts Proportion of IV Proton Pump Inhibitors

Significant reduction in proton pump inhibitor use, associated institutional costs