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Home Tags Heart / Stroke-Related: High Cholesterol

Tag: Heart / Stroke-Related: High Cholesterol

For patients with type 2 diabetes with low-density lipoprotein cholesterol levels <2.0 mmol/L

Higher HDL-C Linked to Cardiac Risk With LDL-C <2.0 mmol/L

Increased risk for cardiovascular events and all-cause mortality for patients with type 2 diabetes
ASGR1 mutation carriers have reduced levels of non-high-density lipoprotein cholesterol and reduced risk of coronary artery disease

ASGR1 Mutation Linked to Reduced Levels of Non-HDL-C

Heterozygous mutation carriers have lower levels of non-HDL-C, reduced risk of coronary artery disease
The impact of high-density lipoprotein cholesterol on cardiovascular disease risk is modulated by triglycerides and low-density lipoprotein cholesterol

HDL-C Prediction of Heart Disease Modulated by TG, LDL-C

Cardiovascular disease risk higher when low HDL-C accompanied by high triglycerides, LDL-C
Expert consensus guidance has been issued regarding the use of non-statin therapies to lower cholesterol in high-risk patients. The consensus document was published online April 1 in the Journal of the American College of Cardiology to coincide with presentation at the annual meeting of the American College of Cardiology

ACC: Expert Guidance Issued for Use of Non-Statin Therapies

Authors recommend addition of ezetimibe at 10 mg/day for higher-risk patients
Familial hypercholesterolemia mutations are seen in less than 2 percent of individuals with low-density lipoprotein cholesterol ≥190 mg/dL

ACC: Prevalence of Familial Hypercholesterolemia <2 Percent

For any given observed LDL cholesterol level, increased risk for CAD for FH mutation carriers
The "Paleo diet" may help older women lose weight

ENDO: ‘Paleo’ Diet May Benefit Heart Health Post Menopause

Trendy eating plan may cut cholesterol, disease risks in postmenopausal women
Familial hypercholesterolemia affects about one in every 250 American men and women and significantly increases their risk for an early heart attack

Familial Hypercholesterolemia More Common Than Thought

Researchers find roughly 834,500 Americans have inherited condition
Some clinical departments tend to undertreat when prescribing statins

Many Physicians Show Tendency to Undertreat With Statins

Target levels more likely to be achieved in departments that prescribe more statins
The U.S. Preventive Services Task Force (USPSTF) has found that current evidence is insufficient for determining the balance of benefits and harms of lipid disorder screening in children

Two Draft Statements From USPSTF Open for Comment

Insufficient evidence for lipid screening in children; recommendation for statins varies with age, risk
For statin-intolerant patients with dyslipidemia with ischemic heart disease treated with percutaneous coronary intervention

Nutraceuticals Alone or With Ezetimibe Aid in Dyslipidemia

Improvement in lipid profile for nutraceuticals alone or in combo for statin-intolerant patients