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Genetic Diagnosis May Aid Management of Pediatric Epilepsy

Establishing a genetic diagnosis for patients with unexplained infantile or childhood-onset epilepsy can help individualize treatment

Delay to Diagnosis of Nonmotor Seizures Longer in Youth

Delays tied to more seizures prior to diagnosis, conversion to motor-type seizures, potentially preventable injuries

Whole-Plant Cannabis Effective, Tolerated for Pediatric Epilepsy

86 percent reduction seen in seizure frequency for children with intractable epilepsy, with no significant adverse events

Hypertension May Increase Risk for Late-Onset Epilepsy

After adjustment for prevalent and interim stroke, risk for developing epilepsy increased almost twofold

Oxcarbazepine Tied to Nontrauma Fracture in Children Aged 4 to 13 With Epilepsy

Initiating oxcarbazepine, but not levetiracetam, linked to increased incidence rate ratio for nontrauma fracture

Some Newer Antiseizure Meds May Not Increase Suicide Risk

Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited

Cognitive Outcomes Studied for In Utero Exposure to Antiseizure Meds

No significant differences in language development seen at age 2 years for children born to mothers with epilepsy

AAN: Fetal Exposure to Antiseizure Meds Has No Neuropsychological Impact

No difference found in primary outcome of Verbal Index score at age 3 years with fetal exposure to ASM or for those born to healthy women

Incidence of Restless Leg Syndrome High in Pregnancy

Seizure Frequency Not Up in Pregnancy for Women With Epilepsy

Changes in doses of antiepileptic drugs occurred more often in pregnant women than in nonpregnant controls

MRI-Guided Laser Therapy Aids Drug-Resistant Pediatric Epilepsy

Laser Therapy Promising for Drug-Resistant Child Epilepsy

Permanent neurological deficits infrequent in follow-up among 129 children receiving MRI-guided laser therapy